Research
Scientists and clinicians working together to beat cancer.
The Edinburgh Cancer Research is a part of the Institute of Genetics and Cancer, however, in addition to scientists based at the IGC, our cancer research is carried out at other University of Edinburgh sites (our affiliates) or NHS Lothian locations.
A broad spectrum of tumor types are studied by our investigators and we aspire to be world class in key themes, bringing innovation and unique twists to basic cancer science, drug development and clinical translation.
Some areas studied by our researchers include:
- The state of the host: lifestyle, risk and prevention
- Stem cells and the cancer niche
- Signal transduction and biological mechanisms
- Phenomics Drug Discovery, incorporating advanced imaging, pathway profiling and novel informatics solutions
- Stratification for therapy
Clinical/translational emphasis is largely in colorectal cancer, women’s cancers (breast, ovarian and endometrial), and more recently in brain cancer, but we have also initiated new research programmes in three new cancer types; sarcoma, renal cancer and intrahepatic cholangiocarcinoma, a poorly researched cancer of unmet need.
Mark Arends
Colorectal Cancer Pathology
Kathryn Ball
Proteostasis and Immune Signalling in Cancer and Dementia
Nezha Benabdallah
Chromatin Regulators in Cancer
Paul Brennan
Brain Tumour Research Group
Gerry Brien
Chromatin Biochemistry and Epigenetics
Ewan Brown
Melanoma and Colorectal Cancer
Val Brunton
Signalling and the regulation of cancer growth and metastasis
David Cameron
Clinical Trials in Breast Cancer
Neil Carragher
Drug Discovery
Sally Clive
Colorectal cancer and Cancers of Unknown Primary
Vincenzo D’Angiolella
Ubiquitin signaling in brain cancer
Farhat Din
Metabolism and Energy Signalling in Colorectal Cancer
Mike Dixon
Edinburgh Breast Unit Research Group
Malcolm Dunlop
Colon Cancer Genetics
Marie Fallon
Edinburgh Palliative and Supportive Care Group (EPAS)
Susan Farrington
Colorectal Cancer Genetics
Margaret Frame
Adhesion networks in cancer
Noor Gammoh
Brain Cancer Survival Pathways
Charlie Gourley
Nicola Murray Centre for Ovarian Cancer Research
Robin Grant
Causes, Treatment and Management of Glioma
Peter Hall
Clinical Informatics and Health Economics in Cancer
Larry Hayward
Sarcoma and Breast Cancer
Simon Herrington
Molecular Cancer Pathology
Robb Hollis
Molecular defects in ovarian cancers
Ted Hupp
Next Generation Technologies for Drug Discovery In Cancer
Ian Kunkler
Clinical and Translational Studies of Breast Radiotherapy
Barry Laird
Improving the Care of Patients with Cancer
Simon Langdon
Targeting ovarian and breast cancer cell signalling pathways
Kevin Myant
Colorectal Stem Cell Transformation
Olga Oikonomidou
Clinical Translational Research in Breast Cancer
Steven Pollard
Neural Stem Cells and Brain Cancer
Bin-Zhi Qian
Tumour Microenvironment in Cancer Metastasis and Therapy Resistance
Dirk Sieger
In Vivo Studies of Microglia-glioma Interactions
Duncan Sproul
Cancer Epigenetics
Lesley Stark
NF-kB - Nucleolar Signalling
Stefan Symeonides
Drug Development and Early Phase Cancer Trials
Evropi Theodoratou
Colorectal Cancer Epidemiology
Jeremy Thomas
Breast Cancer
Arran Turnbull
Translational Oncology Research Group – Breast Cancer
Asier Unciti-Broceta
Innovative Therapeutics
Alexander von Kriegsheim
Network Biology and Proteomics
Simon Wilkinson
Autophagy in Tissue Homeostasis and Cancer
Alan Serrels
Tumour Immune Environment
Tim Aitman (Affiliate)
Diagnosis of rare recessive disease by exome sequencing
Ahsan Akram (Affiliate)
Imaging in Lung Cancer for treatment stratification
Linda Bauld (Affiliate)
Public Health
Luke Boulter (Affiliate)
Signalling in Tissue Repair and Cancer
Hilary Critchley (Affiliate)
Endometrial Biology and Menstrual Related Bleeding Complaints
Andy Downes (Affiliate)
Label-free Optical Spectroscopy and Imaging
Elaine Dzierzak (Affiliate)
Laboratory for Haematological Regeneration
Sara Erridge (Affiliate)
NHS Clinical Oncologist specialising in Neuro-Oncology
Ailith Ewing (Affiliate)
Evolutionary trajectories of structural variation in cancer
Yi Feng (Affiliate)
Cancer prevention - in vivo models of tumour initiation
Jonine Figueroa (Affiliate)
Molecular Epidemiology of Cancer
Stuart Forbes (Affiliate)
Liver Regeneration and Cholangiocarcinoma
Alison Hulme (Affiliate)
Synthesis and Chemical Biology
Katrin Ottersbach (Affiliate)
Developmental Origins of Blood Stem Cells and Leukaemia
Ava Khamseh (Affiliate)
Biomedical Artificial Intelligence
Liz Patton (Affiliate)
Melanocyte Development and Melanoma
Philippa Saunders (Affiliate)
Sex Steroid Hormone Action in Reproductive Health and Disease
Gerry Thompson (Affiliate)
Neuroimaging research
Adam Waldman (Affiliate)
Imaging Biomarkers in Adult Glioma
Sarah Walmsley (Affiliate)
Hypoxic regulation of neutrophilic inflammation