Cancer Research Interests
Professor Pollard has performed research in women’s reproductive health for his entire career with a recent emphasis on the mechanisms of action of female sex steroid hormones in controlling cell proliferation and on the tumour microenvironment of breast cancer. In the former program his lab has sought to understand the mechanism of progesterone in negatively regulating oestrogen-induced uterine epithelial cell proliferation and in the preparation of the uterus for blastocyst implantation. In the latter area he has pioneered studies on the role of macrophages and demonstrated that they promote tumour progression and malignancy. His work has focused upon mechanisms behind these pro-tumoral actions of macrophages with a particular emphasis on metastatic disease.
Director of the MRC Centre for Reproductive Health and Group Leader