Cancer Research UK Edinburgh Centre

Noor Gammoh

Brain Cancer Survival Pathways

Dr Noor Gammoh
Dr Noor Gammoh

Research in a Nutshell 

Glioblastoma Multiforme (GBM) is the most common adult brain tumour and one of the most aggressive cancers with a median survival of approximately one year. Understanding survival response processes that fuel cell proliferation and enhance survival in GBM would be crucial to improve treatment strategies. One such process is autophagy, a cellular degradation pathway frequently activated upon various stresses (e.g. nutrient deprivation and genotoxic stimuli). Understanding how autophagy is regulated and can be targeted during treatment are key goals of our laboratory.

 

Research Programme

Noor-Gammoh-group-2017

People

 
Noor Gammoh

Investigator, CRUK Career Development Fellow and UoE Chancellor’s Fellow

Jane Fraser PhD student
Ainara González Cabodevilla Postdoctoral Fellow
Agata Makar

Research Assistant

Joanne Simpson

Postdoctoral Research Fellow

Leo Dudley PhD student

Contact

ngammoh@exseed.ed.ac.uk

Collaborations

  • Dr Steven Pollard, University of Edinburgh
  • Dr Oliver Florey, University of Cambridge
  • Dr Lukas Dow, Weill Cornell Medical College

Partners and Funders

  • Cancer Research UK / Career Development Fellowship / Jan 2017 – Jan 2024
  • The Carnegie Trust for the Universities of Scotland / Research Incentive Grant / Jan 2016 – Dec 2016
  • University of Edinburgh / Chancellor’s Fellowship / Oct 2013 – Sept 2018

Scientific Themes

Brain Cancer, Glioblastoma, Autophagy, Degradation, Therapy, Treatment, ATG, ATG5, ATG16L1, ATG7, FIP200, LC3

Technology Expertise

RCAS glioma mouse model, in vitro lipidation, autophagy assay