Edinburgh Cancer Research

Simon Herrington

Molecular Cancer Pathology

Professor Simon Herrington - Professor of Molecular Pathology of Cancer

Research in a Nutshell 

My main research focus is the development of optical imaging for the early detection of epithelial neoplasia. I have a long-standing optical imaging collaboration with the School of Physics and Astronomy in St Andrews, which focuses on technology that can discriminate between normal and neoplastic cells and tissues. I am part of the Engineering and Physical Sciences Research Council (EPSRC) and MRC Centre for Doctoral Training in Optical Imaging (OPTIMA), through which I have a collaboration with Strathclyde University, and I am also working with Edinburgh Medical Imaging. These collaborations all aim to develop novel optical approaches to cancer diagnosis. I am also part of the Nicola Murray Centre for Ovarian Cancer Research (Prof Charlie Gourley), with current projects including the molecular investigation of high-grade serous carcinoma of the ovary and the characterization of endometrioid and clear cell ovarian carcinomas. I am Editor in Chief of The Journal of Pathology and The Journal of Pathology: Clinical Research. My research interests are aligned with my clinical practice in gynaecological pathology as a Consultant Pathologist with NHS Lothian.



Simon Herrington

Principal Investigator and Professor of Molecular Pathology of Cancer

Emily Southworth PhD student




  • Prof Kishan Dholakia, Physics and Astronomy, University of St Andrews
  • Prof Duncan Graham, Chemistry, University of Strathclyde
  • Edinburgh Medical Imaging

Website links

Partners and Funders

  • Wellcome Trust ISSF2 award (£65K; 2016). Comparative pathology analysis of gene expression in animal and human tissues by high throughput in-situ hybridization (Co-investigator) (with M Arends, M Cheeseman)
  • Medical Research Scotland (£107,677; 2016-2020). Novel theranostic agents for enhanced diagnosis and minimally invasive therapy of cervical cancer (Co-supervisor) (with M Vendrell and Edinburgh Medical Imaging)
  • Medical Research Council (£2.1M; 2015 – 2018): Edinburgh – St. Andrews Consortium for Molecular Pathology, Informatics and Genome Science (Co-investigator and lead for Masters programme in Molecular Pathology) (with T Aitman (PI), D Harrison and others)

Scientific Themes

Cancer, gynaecology, ovary, cervix, optical imaging

Technology Expertise

Pathology, digital pathology, molecular investigation of human tissue