Cancer Research UK Edinburgh Centre

Olga Oikonomidou

Clinical Translational Research in Breast Cancer

Olga Oikonomidou
Dr Olga Oikonomidou - Consultant Medical Oncologist - Senior Clinical Lecturer in Breast Cancer Medicine & Breast Cancer Translational Research Group Leader Dr Oikonomidou’s major on-going interests include clinical and translational research in breast cancer.

Research in a Nutshell

Dr Oikonomidou’s group is developing non-invasive analyses of breast cancer in order to understand better the breats cancer biology, identify potential therapeutic targets in cancer (early and advanced) and identify early a patient’s response to treatment.

 

Research Programme

 

People

 
Olga Oikonomidou Senior Clinical Lecturer in Breast Cancer Medicine & Consultant Medical Oncologist Breast Cancer Translational Research Group Leader & Principal Investigator

Natalie Wilson

Tissue Consenter/Processor
Sana Shabbir PhD student
Fiona Semple Senior Post Doctoral Fellow

Contact

Olga.Oikonomidou@ed.ac.uk

Collaborations

  • Department of Oncology-Pathology, Karolinska Institutet Breast Center, Karolinska University Hospital
  • Institute of Biological Chemistry, Biophysics and Bioengineering, Nasmyth Building, Heriot-Watt University
  • Centre of Cardiovascular Science, University of Edinburgh

Partners and Funders

  • BCI grant (£100,000) September 2019 Co-PI: Genomics of Endocrine Therapy Resistance – Tailoring Treatment using Personalised Genomic Analysis 
  • Make2ndsCount (£190,000) June 2019 PI: Identification of biomarkers of response to CDK4/6 inhibitors in cfDNA sequential samples from patients with secondary breast cancer. November 2019 
  • CRUK Early Cancer Detection initiative (£475K) Co-Inv: ‘’ Multiplex methylation analysis of cell-free DNA for early cancer diagnosis. February 2018.  
  • NIHR National Institute for Health Research £781K (EME) Co-PI: “Cardiac CARE: A multicentre prospective randomised open-label blinded end-point controlled trial of cardiac troponin guided combination angiotensin receptor blockade and beta blocker therapy to prevent cardiac toxicity in anthracycline treated breast cancer patients”, 3.5 years from September 2017.  
  • Chief Scientist Office Research Grant (£220,883) Co-PI : Novel sample preparation for improved circulating tumour DNA analysis. 3 years from July 2015. 
  • MRC Confidence in Concept Scheme - Translation of Medical Informatics (£60,000) PI: Bioinformatics analysis of the NEO pilot study. 2 years from May 2014. 
  • CRUK Grant-Development Fund (£25,000) PI:  for ‘’The NEO study: a study of factors predicting response to neoadjuvant chemotherapy in breast cancer patients’’. April 2014. 
  • University of Edinburgh Internal fund (£40,000) Co-PI: the role of Magnetic Resonance Phosphorous Spectroscopy (31P-MRS) in detecting changes in heart function associated with the use of chemotherapy drugs used to treat breast cancer. December 2014. 

 

If you are interested to make a donation to translational breast cancer research please get in touch with  

Leisa Thomas 

Senior Philanthropy Officer, Health, Medicine and Veterinary Medicine 

0131 651 4403

leisa.thomas@ed.ac.uk

www.ed.ac.uk/development-alumni

 

Scientific Themes

Breast cancer, Translational studies, Genomics, Transcriptomics, cfDNA, DNA methylation, Personalised Medicine.

Technology Expertise

Trascriptomics, ddPCR, Sanger Sequencing.