Katrin Ottersbach (Affiliate)
Developmental Origins of Blood Stem Cells and Leukaemia
Research in a Nutshell
Our group is studying leukaemia in infants as a unique, developmental disease. Complementing our other interests in how blood cells are generated during development, we are trying to understand how the properties of the foetal cell-of-origin in infant leukaemia dictates the disease phenotype and the implications this has for designing treatment strategies that are specifically tailored to the requirements of infant patients.
People |
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| Katrin Ottersbach | Principal Investigator and Senior Lecturer and UoE Chancellor’s Fellow |
| Camille Malouf | Postdoc |
| Chrysa Kapeni | Research Assistant and PhD student |
| Nada Zaidan | PhD student |
| Vasiliki Symeonidou | PhD student |
Contact
Collaborations
- Professor Bertie Göttgens, Department of Haematology, University of Cambridge, UK
- Dr Simon Tomlinson, MRC Centre for Regenerative Medicine, University of Edinburgh, UK
- Dr Patrick Case, University of Bristol, UK
- Professor Kamil Kranc, MRC Centre for Regenerative Medicine, University of Edinburgh, UK
Partners and Funders (current)
- Bloodwise/Senior Bennett Fellowship/Sep 2011 - Dec 2016/£809,360
- Kay Kendall Leukaemia Fund/Project grant/Sep 2014 - Aug 2016/£136,449
- University of Edinburgh/Chancellor's Fellowship/Mar 2015 – Aug 2017/£180,000
- Wellcome Trust-University of Edinburgh/Strategic Support Fund/Jun 2016 - Feb 2017/£50,000
Scientific Themes
Blood stem cells, developmental haematopoiesis, infant leukaemia, MLL-AF4, miRNAs
Technology Expertise
Leukaemia mouse models, transplantation assays, haematopoietic assays