Edinburgh Cancer Research

Charlie Gourley

Nicola Murray Centre for Ovarian Cancer Research

Professor Charlie Gourley - Chair of Medical Oncology and Honorary Consultant in Medical Oncology; Clinical Director, CRUK Scotland Centre; Director, Nicola Murray Centre for Ovarian Cancer Research

Research in a Nutshell 

Ovarian cancer is the sixth most common cause of female cancer death in the UK. Until recently it has been treated as a single disease entity. There is now considerable evidence to demonstrate that ovarian cancers differ in their tissues of origin, their genetic abnormalities, their responsiveness to chemotherapy and the ultimate outcome for patients. 

We are investigating the biology of this disease at the interface between the laboratory and the clinic in order to generate findings that can be directly translated into patient benefit. We do this by characterising the molecular changes that occur in different ovarian cancers and determining how this affects their responsiveness to chemotherapy or novel biological agents


Research Programme

Nicola Murray Foundation 

Charlie Gourley Research Group (Left to right: Charlie Gourley, Mike Churchman, John Thomson, Ian Croy, Lorna, Ailsa Oswald and Rosie Matthews).
Charlie Gourley Research Group (Left to right: Charlie Gourley, Mike Churchman, John Thomson, Ian Croy, Lorna, Ailsa Oswald and Rosie Matthews).
Nicola Murray Foundation



Charlie Gourley

Principal Investigator, Professor of Medical Oncology; Translational Lead CRUK Scotland Centre; Director of the Nicola Murray Centre for Ovarian Cancer Research

Mike Churchman Lab Manager
Jessica Lim ECAT Clinical Research Fellow
John Thomson Research Fellow
Ian Croy Histology Technician
Lorna Stillie TRACC Programme MB-PhD student
Ailsa Oswald AZ-CRUK TRACC Clinical Research Training Fellow
Rosie Matthews Research Assistant

Laboratory Collaborations

Robb Hollis IGC Langmuir Talent Fellow
Molecular Cancer Pathology
Simon Herrington

Professor of Molecular Pathology

Emily Southworth PhD student
Ovarian and breast cancer signalling group
Simon Langdon Reader
Sarah Taylor PhD student
Targeting developmental cell states in melanoma
Liz Patton

Group Leader/Personal Chair of Chemical Genetics

Zahra Massoud PhD Student
Clinical Informatics and Health Economics in Cancer
Peter Hall Senior clinical lecturer in Cancer Informatics
Grant Cameron Database assistant
David Melton Emeritus Professor



PA: laura.wood@ed.ac.uk


  • International Consortium for Low-Grade Serous Ovarian Cancer  (ICLC): The University of Texas M. D. Anderson Cancer Centre, Memorial Sloan Kettering Cancer Centre, Johns Hopkins University, The University of Sydney, The Westmead Institute for Medical Research, Centre Leon Berard, BC Cancer, part of Provincial Health Services Authority, University of Otago, and the University of Edinburgh
  • Cancer Research-UK Scotland Centre, UK (Edinburgh and Glasgow Ovarian Cancer Group): Prof Owen Samson, Dr Patricia Roxburgh, Dr Ros Glasspool, Dr Seth Coffelt, Dr David Millan and Dr Gareth Bryson.
  • Cancer Research-UK Scotland Centre/ Wellbeing of Women/Artios: Dr Patricia Roxburgh
  • Stanford Women Cancer Centre, Stanford University. Stanford, California: Professor Amer Karam
  • Peter MacCallum Cancer Centre, Melbourne, Australia: Professor Ian Campbell and Dr Kylie Gorringe.
  • University of Sydney, Sydney, Australia: Professor Anna de Fazio.
  • Netherlands Cancer Institute, Amsterdam, Netherlands: Dr Christianne Lok.
  • The University of Texas MD Anderson Cancer Centre: Professor David M. Gershenson, MD

Partners and Funders

  • Nicola Murray foundation: Charitable donation
  • Cancer Research UK: Core funding, research grants and PhD fellowships.
  • Wellbeing of Women/Artios: Research Grant
  • University College London Clinical Trials Unit/Cancer Research-UK/Astra Zeneca: ICON9 clinical trial and related translational research
  • AstraZeneca/Scottish Chief Scientist Office/Scottish Genome Partnership: Research grant.
  • Medannex Ltd: Research Grant
  • Target Ovarian Cancer: Research Grant

Scientific Themes

Ovarian cancer genomics and transcriptomics, translational research