Cancer Research UK Edinburgh Centre

Susan Farrington

Colorectal Cancer Genetics

Dr Susan Farrington
Dr Susan Farrington - Reader

Research in a Nutshell 

The overall aim is to target appropriate clinical screening to those people most at risk of developing colorectal cancer, as this has proven efficacy. This can only be done, by better understanding of the risk factors associated with the disease, both at the genetic/heritable level and environmental factors influencing disease and indeed the ways they can interact and modify disease risk. Identification of the pathways involved in tumour initiation and progression using model systems, will help us further our ability to stratify screening by risk.

 

Research Programme

 

S.Farrington group

People

 
Susan Farrington Principal Investigator and Reader
Anna-Maria Ochocka Research Fellow
Vidya Rajasekaran Research Fellow
Victoria Svinti Bioinformatician
Maria Timofeeva Statistician (shared role: Farrington and Dunlop)
Marion Walker Laboratory Manager
Stuart Reid Research Technician
Ruby Osborn PhD student
Peter Vaughan-Shaw Clinical Research PhD student
Paz Friele   (shared role:  Farhat Din/Susan Farrington/Malcolm Dunlop/Mark Arends/ Kevin Myant)

Collaborations

  • Professor Malcolm Dunlop, University of Edinburgh
  • Professor Harry Campbell, University of Edinburgh
  • Dr Farhat Din, University of Edinburgh
  • Professor Colin Semple, University of Edinburgh
  • Dr Evropi Theodoratou, University of Edinburgh
  • Professor Mark Arends, University of Edinburgh
  • Professor Martin Taylor, University of Edinburgh
  • Professor Ian Jackson, University of Edinuburgh 
  • Dr Carmel Moran, University of Edinburgh 
  • Professor Albert Tenesa, University of Edinburgh
  • Dr Lina Zgaga, University College Dublin
  • Professor Ian Tomlinson, University of Oxford
  • Professor Richard Houlston, ICR
  • Professor Maurizio Genuardi via InSiGHT variant Interpretation Committee

Partners and Funders

  • CRUK/Programme/5yrs/£3.3M
  • MRC/Project/3yrs/£1.1M
  • Melville Trust/Project/1yr/£8.1K

Scientific Themes

Colorectal cancer, genetics, environmental, mechanisms of risk, risk stratification, models of risk alleles

Technology Expertise

Genomics approaches (GWAS, eQTL analysis)