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Dr Gerry McLachlan

Dr Gerry McLachlan

Group Leader/Senior Research Fellow

Highlighted Publications

Microbiota in Exhaled Breath Condensate and the Lung

Laura Glendinning, Steven Wright, Peter Tennant, Andrew C Gill, David Collie, Gerry McLachlan Applied and Environmental Microbiology Vol: 83 Jun 2017

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Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis

Alan Boyd, Heather Davidson, Ann Doherty, Laura Hyndman, Gerry McLachlan, James Alastair Innes, Barbara Stevenson and 31 others Thorax Vol: 72 Pages: 137-147 Feb 2017

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Variability of the Sheep Lung Microbiota

Laura Glendinning, Steven Wright, Jolinda Pollock, Peter Tennant, David Collie, Gerry McLachlan Applied and Environmental Microbiology Vol: 82 Pages: 3225-3238 Jun 2016

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Lung Microbiota Changes Associated with Chronic Pseudomonas aeruginosa Lung Infection and the Impact of Intravenous Colistimethate Sodium

David Collie, Laura Glendinning, John Govan, Steven Wright, Elisabeth Thornton, Peter Tennant, Catherine Doherty, Gerry McLachlan PLoS ONE Vol: 10 Pages: e0142097 07 Nov 2015

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Repeated nebulisation of non-viral CFTR gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial

A Christopher Boyd, D David S Collie, Steve Cunningham, Heather E Davidson, Ann Doherty, Laura Hyndman, Alan W Maclean, Dominique Mccormick, Michael Mcgovern, Gerry Mclachlan, Gordon D Murray, David J Porteous, Keith Smith, Barbara J Stevenson and 66 others The Lancet Respiratory Medicine Vol: 3 Pages: 684-691 01 Jul 2015

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The safety profile of a cationic lipid-mediated cystic fibrosis gene transfer agent following repeated monthly aerosol administration to sheep

E. W. Alton, Alison Baker, Eilidh Baker, Christopher Boyd, S. H. Cheng, Rebecca Coles, David Collie, Heather Davidson, Jane C Davies, D. R. Gill, Catherine Gordon, U. Griesenbach, T. Higgins, S. C. Hyde, J. A. Innes, Dominique McCormick, Michael McGovern, Gerry McLachlan, David Porteous, I. A. Pringle, R. K. Scheule, Darren Shaw, Sionagh Smith, Stephanie Summer-Jones, Peter Tennant, Christina Vrettou Biomaterials Vol: 34 Pages: 10267-10277 2013

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A Lung Segmental Model of Chronic Pseudomonas Infection in Sheep

David Collie, John Govan, Steven Wright, Elisabeth Thornton, Peter Tennant, Sionagh Smith, Catherine Doherty, Gerry McLachlan PLoS ONE Vol: 8 09 Jul 2013

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Pre-clinical evaluation of three non-viral gene transfer agents for cystic fibrosis after aerosol delivery to the ovine lung

G McLachlan, H Davidson, E Holder, L A Davies, I A Pringle, S G Sumner-Jones, A Baker, P Tennant, C Gordon, C Vrettou, R Blundell, L Hyndman, B Stevenson, A Wilson, A Doherty, D J Shaw, R L Coles, H Painter, S H Cheng, R K Scheule, J C Davies, J A Innes, S C Hyde, U Griesenbach, E W F W Alton, A C Boyd, D J Porteous, D R Gill, D D S Collie Gene Therapy Vol: 18 Pages: 996-1005 2011

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Validation of recombinant Sendai virus in a non-natural host model

U. Griesenbach, G. McLachlan, T. Owaki, L. Somerton, T. Shu, A. Baker, P. Tennant, C. Gordon, C. Vrettou, E. Baker, D. D. S. Collie, M. Hasegawa, E. W. F. W. Alton Gene Therapy Vol: 18 Pages: 182-188 Feb 2011

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Secreted Gaussia luciferase as a sensitive reporter gene for in vivo and ex vivo studies of airway gene transfer

Uta Griesenbach, Catarina C. Vicente, Megan J. Roberts, Cuixiang Meng, Samia Soussi, Stefania Xenariou, Peter Tennant, Alison Baker, Eilidh Baker, Catherine Gordon, Christina Vrettou, Dominique McCormick, Rebecca Coles, Anne-Marie Green, Anna E. Lawton, Stephanie G. Sumner-Jones, Seng H. Cheng, Ronald K. Scheule, Stephen C. Hyde, Deborah R. Gill, David D. Collie, Gerry McLachlan, Eric W. F. W. Alton Biomaterials Vol: 32 Pages: 2614-2624 Apr 2011

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Enhanced lung gene expression after aerosol delivery of concentrated pDNA/PEI complexes

Lee A. Davies, Gerry McLachlan, Stephanie G. Sumner-Jones, David Ferguson, Alison Baker, Peter Tennant, Catherine Gordon, Christina Vrettou, Eilidh Baker, Jie Zhu, Eric W. F. W. Alton, David D. S. Collie, David J. Porteous, Stephen C. Hyde, Deborah R. Gill Molecular Therapy Vol: 16 Pages: 1283-1290 Jul 2008

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