Current projects

INVESTIGATE-SVDs

Imaging NeuroVascular, Endothelial & STructural Integrity in prepAration to TrEat Small Vessel Diseases

• A MRI study at 3T to assess blood brain barrier function, microvascular function, & perivascular flow.

LACunar Intervention Trial-2

• Assessment of safety & efficacy of cilostazol & isosorbide mononitrate to prevent recurrent lacunar stroke & progression of cerebral small vessel disease.

• Investigate the role of the enlarged perivascular space (PVS) in cerebral small vessel disease (SVD).

Mild Stroke Study 3

• Improve understanding of what makes small vessel disease (SVD) worsen (or perhaps improve) & identify novel targets for SVD prevention & therapy.

SVDs@target

• Develop novel therapeutic treatments & finally contribute to the prevention of stroke & dementia

TREAT-SVDs

•  An interventional study to determine the effects of different blood pressure lowering agents on microvascular function in patients with distinct SVDs.