Centre for Inflammation Research

Clinical trials

Find out about our current clinical studies, which are trying to understand the underlying mechanisms of disease and potential treatments for various inflammatory diseases including COVID-19

Current trials associated with the Centre are listed below. Trials run directly from the Centre are highlighted in blue, with trials run by external organisations in white.

GuARDS Trial

A UK-wide clinical trial involving 65 hospitals, exploring dexamethasone treatment in patients with acute respiratory distress syndrome (ARDS).

TRAITS - Time Critical Precision Medicine programme

TRAITS - Enabling Precision Medicine for Intensive Care | Treatable Traits | Clinical Trial | Biology
TRAITS is a precision medicine research programme in critically ill adults.


Logo for the DEFINE study
DEFINE is a clinical study which aims to test promising new therapies in small numbers of COVID-19 patients.


Graphic showing two people being sorted into trial groups, with and without Camostat.
SPIKE-1 is a Phase 2/3 trial looking at the use of Camostat to reduce the progression of symptoms of coronavirus (COVID-19).


RESORP Logo - Resolution of organ injury in acute pancreatitis
The Resolution of Organ Injury in Acute Pancreatitis (RESORP) trial seeks to understand why patients with acute pancreatitis either recover or require intensive care.

Crohn's and colitis trials

Inflammation of the gut in Crohn's disease and colitis, highlighted in red on a blue human body
CIR clinical trials for the discovery of new treatments and targets for Inflammatory Bowel Diseases (IBD) including Crohn's disease and ulcerative colitis.

Further contributions to clinical trials


The SPIRIT-Path project aims to improve clinical trials involving pathology samples by developing International Guidance on the Inclusion of Pathology in Clinical Trial Protocols. It aims to create transparent, systematic methods to improve the quality and consistency of pathology-based research. Dr Tim Kendall is co-Chair of this study.

Learn more about SPIRIT-Path

Trial management

Our clinical trials are managed through the Academic and Clinical Central Office for Research and Development (ACCORD), a partnership between the University of Edinburgh and NHS Lothian Health Board.

Accord Logo

Visit the ACCORD website