Clinical trials

Find out about our current clinical studies, which are trying to understand the underlying mechanisms of disease and potential treatments for various inflammatory diseases including COVID-19

Current trials associated with the Centre are listed below. Trials run directly from the Centre are highlighted in blue, with trials run by external organisations in white.

GuARDS Trial

A UK-wide clinical trial involving 65 hospitals, exploring dexamethasone treatment in patients with acute respiratory distress syndrome (ARDS).

TRAITS - Time Critical Precision Medicine programme

TRAITS is a precision medicine research programme in critically ill adults.

DEFINE COVID-19

DEFINE is a clinical study which aims to test promising new therapies in small numbers of COVID-19 patients.

SPIKE-1

SPIKE-1 is a Phase 2/3 trial looking at the use of Camostat to reduce the progression of symptoms of coronavirus (COVID-19).

RESORP

The Resolution of Organ Injury in Acute Pancreatitis (RESORP) trial seeks to understand why patients with acute pancreatitis either recover or require intensive care.

Crohn's and colitis trials

CIR clinical trials for the discovery of new treatments and targets for Inflammatory Bowel Diseases (IBD) including Crohn's disease and ulcerative colitis.

Further contributions to clinical trials

SPIRIT-Path

The SPIRIT-Path project aims to improve clinical trials involving pathology samples by developing International Guidance on the Inclusion of Pathology in Clinical Trial Protocols. It aims to create transparent, systematic methods to improve the quality and consistency of pathology-based research. Dr Tim Kendall is co-Chair of this study.

Learn more about SPIRIT-Path

Trial management

Our clinical trials are managed through the Academic and Clinical Central Office for Research and Development (ACCORD), a partnership between the University of Edinburgh and NHS Lothian Health Board.

Visit the ACCORD website