Centre for Clinical Brain Sciences

Prion disease

Incidence and diagnosis, cellular mechanisms and pathogenesis of Creutzfeldt-Jakob disease and other prion diseases.

Large florid plaque in the cerebral cortex in variant CJD a florid CJD plaque

The clinical neurologists, neuropathologists and scientists at the National CJD Research and Surveillance Unit, in collaboration with the Roslin Institute, monitor the characteristics of CJD, identify trends in incidence, study risk factors and contribute to improving the quality of care for those with CJD.



Prion disease projects and services
Research theme PI
Diagnostic services and the development of new diagnostic tests & biomarkers Alison Green
Molecular and cellular aspects of protein misfolding Mark Head
Mechanisms of neurodegeneration and neuroprotection Jean Manson
CJD epidemiology, clinico-pathological characterisation, diagnostics & public health Richard Knight
Neuropathological phenotype, distribution of abnormal prion protein & neurodegenerative pathology James Ironside
Epidemiology, surveillance & public health Anna Molesworth
Diagnosis, epidemiology & public health Robert Will

Related Links

National CJD Research and Surveillance Unit

The Roslin Institute