Edinburgh Clinical Trials

Relevant Research

List of current literature relevant to the CARE trial

Relevant publications

Publication Link to publication

Priorities for research

Top ten research priorities for brain and spine cavernous malformations

Read online
Comparative studies of the diagnosis and treatment of cerebral cavernous malformations in adults: systematic review Read Online

Treatment without surgery

Clinical course of untreated cerebral cavernous malformations: a meta-analysis of individual patient data Read online
Seizure risk from cavernous or arteriovenous malformations - Prospective population-based study Read Online

Treatment with neurosurgery

Surgery for cerebral cavernous malformations: a systematic review and meta-analysis

Read Online
A systematic review and meta-analysis of surgeries performed for treating deep-seated cerebral cavernous malformations Read Online
Outcomes of Surgery for Brainstem Cavernous Malformations: A Systematic Review Read Online
Microsurgery vs. Gamma Knife Radiosurgery for the Treatment of Brainstem Cavernous Malformations: A Systematic Review and Meta-Analysis Read Online

Treatment with stereotactic radiosurgery

Stereotactic radiosurgery for cerebral cavernous malformations: A systematic review Read Online
Stereotactic Radiosurgery for Brainstem Cavernous Malformations: An Updated Systematic Review and Meta-Analysis Read Online


Synopsis of Guidelines for the Clinical Management of Cerebral Cavernous Malformations: Consensus Recommendations Based on Systematic Literature Review by the Angioma Alliance Scientific Advisory Board Clinical Experts Panel Read Online
Cavernoma-related epilepsy: review and recommendations for management--report of the Surgical Task Force of the ILAE Commission on Therapeutic Strategies Read Online



Other ongoing randomised trials in cavernoma research

Trial Name Further information
AT CASH EPOC Trial information
Treat_CCM Trial information

Further information about treatments for cavernoma that may enter clinical trials in the future.