Dr Erin Williams
Senior Lecturer in Reproductive Anatomy & Physiology
Contact details
Address
- Street
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The Royal (Dick) School of Veterinary Studies and The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Availability
Willingness to take Ph.D. students: Yes
Responsibilities & affiliations
- R(D)SVS Academic Lead for Tutors & Demonstrators
- Society for Reproduction and Fertility Chair of Education & Public Engagement
- Co-Founder and Director of Feed SC050164
Research summary
Have you ever wondered how the bacteria that live on and inside of us influence how our bodies function? That is the question that the Williams lab aims to answer, with a specific focus on the female reproductive tract and the mammary gland. By identifying the mechanisms by which the microbiome influences female reproductive health and fertility, and how this is altered during disease, our aim is to develop diagnostic and therapeutic strategies to combat the most common and debilitating mammalian reproductive health issues and disorders of lactation.
In a complementary theme, our lab also investigates the social and political factors influencing infant feeding in the UK, and the barriers that women face when it comes to feeding their babies.
Current research interests
• The impact of the reproductive tract microbiome on menstruation in women. • The impact of the cost of living crisis on infant feeding in the UK. • Can the vaginal microbiome predict pregnancy success in dairy cattle? • Mechanisms controlling postpartum uterine inflammation and infection in the dairy cow.Current project grants
• Williams EJ. (2022 - 2024). Understanding the impact of Prolactin on postpartum uterine immunity. Society for Reproduction and Fertility, Return to Research Scholarship. Principal Investigator; £9,500.
Past project grants
• Cunha-Carneiro L and Williams EJ (2018-2019). Effect of omega-3 supplementation on reproductive performance and immune response in dairy cows. FAPESP Research Internship Abroad. Principal Supervisor; £12,000.
• Wheelhouse N and Williams EJ. (2018) Does the vaginal microbiome predict pregnancy success in cattle? Napier University Research Funding Competition. Principal Investigator; £9,500.
• Meade KM, Meijer WM, Evans ACO and Williams EJ. (2013-2018) Early diagnosis of postpartum uterine disease for Enhanced Reproduction and Improved Cow Health (ENRICH). Irish Dept. of Agriculture Research Stimulus Fund. Principal Investigator; £1,250,000.
• Carrington SD and Williams EJ. (2013). A predictive test for endometritis in cows for improved reproductive management in dairy herds. Science Foundation Ireland and Enterprise Ireland Joint Technology Innovation Development Award (TIDA). Co-applicant; €96,000.
• Crowe ME et al. (2013) Role of Genotype and Environment in the contribution to dairy cow productivity using a genomics approach (GplusE). EU FP7 consortium. Collaborator; €9,000,000.
• Williams EJ, Berry D and McParland S. (2012). Genetics of reproductive tract ultrasound measurements in dairy and beef cattle. Teagasc Walsh Fellowship Scheme. Co-Applicant; €42,000.
• Williams EJ (2012-2013) Development of a multiplex Real Time PCR for the detection of Campylobacter, E.coli and Salmonella in sheep. UCD Seed Funding Initiative in conjunction with Bofinn Diagnostics Ltd. Principal Investigator; €5,000.
• Williams EJ, Carrington SD and Evans ACO (2011-2012) Development of a uterine health scoring system in postpartum dairy cattle. Enterprise Ireland Innovation Voucher in conjunction with Reprodoc Ltd. Principal Investigator; €5,000.
• Williams EJ and Evans ACO (2011-2012) Evaluation of a novel antimicrobial agent for prevention and treatment of reproductive tract disease. Enterprise Ireland Innovation Voucher in conjunction with Capstan Healthcare Ltd. Principal Investigator; €5,000.
• Williams EJ and Evans ACO (2010-2011) Development of a novel duplex Real Time PCR for the detection of Chlamydophila abortus and Toxoplasma gondii in sheep. Enterprise Ireland Innovation Voucher in conjunction with Bofinn Diagnostics Ltd. Principal Investigator; €5,000.
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A preliminary analysis of the variation in circulating 25-hydroxycholecalciferol concentrations in peri-partum spring-calving dairy cows
In:
Veterinary Research Communications
DOI: https://doi.org/10.1007/s11259-022-09946-z
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Use of a cow-side oestrus detection test for fertility management in Kenyan smallholder dairy herds.
In:
Gates Open Research, vol. 6, pp. 1-16
DOI: https://doi.org/10.12688/gatesopenres.13542.1
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Purulent vaginal discharge diagnosed in pasture-based Holstein-Friesian cows at 21 days postpartum is influenced by previous lactation milk yield and results in diminished fertility
In:
Journal of Dairy Science
DOI: https://doi.org/10.3168/jds.2019-17116
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Delayed differentiation of vaginal and uterine microbiomes in dairy cows developing postpartum endometritis
(23 pages)
In:
PLoS ONE, vol. 14
DOI: https://doi.org/10.1371/journal.pone.0200974
Research output: Contribution to Journal › Article (Published) -
METHODS FOR PREDICTING, DIAGNOSING OR MONITORING INFECTIONS OR CONDITIONS
Research output: › Patent (Published) -
Risk factors associated with detailed reproductive phenotypes in dairy and beef cows
(9 pages)
In:
Animal, vol. 8, pp. 695-703
DOI: https://doi.org/10.1017/S1751731114000354
Research output: Contribution to Journal › Article (Published) -
Parturition to resumption of ovarian cyclicity: Comparative aspects of beef and dairy cows
(14 pages)
In:
Animal, vol. 8, pp. 40-53
DOI: https://doi.org/10.1017/S1751731114000251
Research output: Contribution to Journal › Article (Published) -
Drivers of post-partum uterine disease in dairy cattle
(6 pages)
In:
Reproduction in Domestic Animals, vol. 48, pp. 53-58
DOI: https://doi.org/10.1111/rda.12205
Research output: Contribution to Journal › Article (Published) -
Triennial lactation symposium: Effects of stress on postpartum reproduction in dairy cows
(5 pages)
In:
Journal of Animal Science, vol. 90, pp. 1722-1727
DOI: https://doi.org/10.2527/jas.2011-4674
Research output: Contribution to Journal › Article (Published) -
Detection of Toxoplasma gondii antigens reactive with antibodies from serum, amniotic, and allantoic fluids from experimentally infected pregnant ewes
(9 pages)
In:
Veterinary Parasitology, vol. 185, pp. 91-100
DOI: https://doi.org/10.1016/j.vetpar.2011.10.028
Research output: Contribution to Journal › Article (Published)
Patents:
- United Kingdom Patent Application No. GB1315705.2 "Methods for predicting, diagnosing or monitoring infections" University College Dublin, Ireland. Filed Sept 2013.
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Rudd P, Stöckmann H, Carrington S, Williams EJ, Tharmalingam T, Evans A, inventors; University College Dublin, assignee. Methods for predicting, diagnosing or monitoring infections or conditions. United States patent application US 14/915,969. 2016 Jul 21.
Invention Disclosures:
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Casa-Luengo RM, Williams EJ, Lu J, Evans ACO, Carrington SC, Meijer WG (2014). Identification of Operational Taxonomical Units in bacterial populations of the bovine reproductive tract as prognostic biomarkers for development of postpartum endometritis.
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Williams EJ, Stoeckmann H, Tharmalingham T, Evans ACO, Rudd P and Carrington SC (2013). Glycosylation of blood proteins as a prognostic biomarker for post partum uterine disease in cattle.
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Gutierrez J, Williams EJ, O’Donovan J, Sammin D, Bassett H, Markey BK and Evans ACO. (2009) Development of a novel duplex Real Time PCR for the detection of Chlamydophila abortus and Toxoplasma gondii in sheep.