Publications
Publications from the lab.
A conserved CENP-E region mediates BubR1-independent recruitment to the outer corona at mitotic onset 13 Feb 2024, (E-pub ahead of print) In: Current Biology. 34, 14 p. DOI: https://doi.org/10.1016/j.cub.2024.01.042 Research output: Contribution to journal › Article › peer-review
Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis 2 Nov 2023, In: The EMBO journal. 42, 21, 18 p., e113647. DOI: https://doi.org/10.15252/embj.2023113647 Research output: Contribution to journal › Article › peer-review
Understanding molecular mechanisms and predicting phenotypic effects of pathogenic tubulin mutations 7 Oct 2022 in PLoS Computational Biology DOI: https://doi.org/10.1371/journal.pcbi.1010611 Research output: Contribution to Journal › Article (Published)
Potent microtubule depolymerizing activity of a mitotic Kif18b-MCAK-EB network (25 pages) 31 May 2022 in Journal of Cell Science, vol. 136 DOI: https://doi.org/10.1242/jcs.260144 Research output: Contribution to Journal › Article (Published)
Reconstitution of an active human CENP-E motor (10 pages) 9 Mar 2022 in Open Biology, vol. 12 DOI: https://doi.org/10.1098/rsob.210389 Research output: Contribution to Journal › Article (Published)
The C-terminal helix of BubR1 is essential for CENP-E-dependent chromosome alignment (11 pages) 25 Aug 2020 in Journal of Cell Science, vol. 133 DOI: https://doi.org/10.1242/jcs.246025 Research output: Contribution to Journal › Article (Published)
Reciprocal regulation of aurora kinase A and ATIP3 in the control of metaphase spindle length 13 Aug 2020 in Cellular and Molecular Life Sciences DOI: https://doi.org/10.1007/s00018-020-03614-8 Research output: Contribution to Journal › Article (Published)
Leaving no-one behind: How CENP-E facilitates chromosome alignment (12 pages) 29 Apr 2020 in Essays in biochemistry DOI: https://doi.org/10.1042/EBC20190073 Research output: Contribution to Journal › Review article (Published)
The Role of protein Complexes in Human Genetic Disease 1 Aug 2019 in Protein Science, vol. 28 DOI: https://doi.org/10.1002/pro.3667 Research output: Contribution to Journal › Review article (Published)
A rapid computational approach identifies SPICE1 as an Aurora kinase substrate (12 pages) 31 Jan 2019 in Molecular Biology of the Cell, vol. 30, pp. 312-323 DOI: https://doi.org/10.1091/mbc.E18-08-0495 Research output: Contribution to Journal › Article (Published)
The depolymerase activity of MCAK shows graded response to Aurora B kinase phosphorylation through allosteric regulation (8 pages) 14 Jan 2019 in Journal of Cell Science, vol. 132 DOI: https://doi.org/10.1242/jcs.228353 Research output: Contribution to Journal › Article (Published)
Parts list for a microtubule depolymerising kinesin (8 pages) 22 Nov 2018 in Biochemical Society Transactions DOI: https://doi.org/10.1042/BST20180350 Research output: Contribution to Journal › Review article (E-pub ahead of print)
Microtubule end tethering of a processive kinesin-8 motor Kif18b is required for spindle positioning (14 pages) 2 Jul 2018 in Journal of Cell Biology, vol. 217, pp. 2403-2416 DOI: https://doi.org/10.1083/jcb.201705209 Research output: Contribution to Journal › Article (Published)
Mechanisms of Mitotic Kinase Regulation: A Structural Perspective 5 Feb 2018 in Frontiers in Cell and Developmental Biology, vol. 6, pp. 6 DOI: https://doi.org/10.3389/fcell.2018.00006 Research output: Contribution to Journal › Article (Published)
Inhibition of ectopic microtubule assembly by the kinesin-13 KLP-7 prevents chromosome segregation and cytokinesis defects in oocytes (13 pages) 1 May 2017 in Development, vol. 144, pp. 1674-1686 DOI: https://doi.org/10.1242/dev.147504 Research output: Contribution to Journal › Article (Published)
Molecular architecture of the Dam1 complex-microtubule 1 interaction 9 Mar 2016 in Open Biology, vol. 6 DOI: https://doi.org/10.1098/rsob.150237 Research output: Contribution to Journal › Literature review (Published)
Overlap microtubules link sister k-fibres and balance the forces on bi-oriented kinetochores 5 Jan 2016 in Nature Communications, vol. 7 DOI: https://doi.org/10.1038/ncomms10298 Research output: Contribution to Journal › Article (Published)
The C-terminal region of the motor protein MCAK controls its structure and activity through a conformational switch (55 pages) 27 Apr 2015 in eLIFE, vol. 4 DOI: https://doi.org/10.7554/eLife.06421 Research output: Contribution to Journal › Article (Published)
Length-dependent anisotropic scaling of spindle shape (7 pages) 2014 in Biology Open, vol. 3, pp. 1217-23 DOI: https://doi.org/10.1242/bio.201410363 Research output: Contribution to Journal › Article (Published)
Cell Cycle Regulation of Microtubule Interactomes: Multi-layered Regulation Is Critical for the Interphase/Mitosis Transition (13 pages) Nov 2013 in Molecular & Cellular Proteomics (MCP), vol. 12, pp. 3135-47 DOI: https://doi.org/10.1074/mcp.M113.028563 Research output: Contribution to Journal › Article (Published)
The molecular basis for kinesin functional specificity during mitosis (18 pages) Sep 2013 in Cytoskeleton, vol. 70, pp. 476-93 DOI: https://doi.org/10.1002/cm.21135 Research output: Contribution to Journal › Article (Published)
The microtubule-binding protein Cep170 promotes the targeting of the kinesin-13 depolymerase Kif2b to the mitotic spindle (10 pages) 15 Dec 2012 in Molecular Biology of the Cell, vol. 23, pp. 4786-4795 DOI: https://doi.org/10.1091/mbc.E12-03-0214 Research output: Contribution to Journal › Article (Published)
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