Dr Grzegorz Kudla
Group Leader
- MRC Human Genetics Unit
- MRC Institute of Genetics & Molecular Medicine
Contact details
- Email: grzegorz.kudla@igmm.ed.ac.uk
Background
Grzegorz Kudla is a group leader at the MRC Human Genetics Unit, University of Edinburgh, Edinburgh, Scotland. He received his PhD in 2005, in the Maciej Zylicz lab, International Institute of Molecular and Cell Biology, Warsaw, Poland. He then worked as a postdoc with Joshua Plotkin at Harvard University and with David Tollervey at the University of Edinburgh, to study the influence of codon bias on gene expression. He is currently developing experimental and bioinformatic tools to study regulation of gene expression, protein-RNA interactions, and RNA-RNA interactions. Since 2008 he has served as Academic Editor of the open access journal PLoS ONE.
Qualifications
PhD in Biochemistry, 2005, International Institute of Molecular and Cell Biology, Warsaw, Poland
MSc in Animal Physiology, 2000, Warsaw University, Warsaw, Poland
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Codon usage influences fitness through RNA toxicity
In:
Proceedings of the National Academy of Sciences (PNAS)
DOI: https://doi.org/10.1073/pnas.1810022115
Research output: Contribution to Journal › Article (Published) -
Strand-specific, high-resolution mapping of modified RNA polymerase II
In:
Molecular Systems Biology, vol. 12
DOI: https://doi.org/10.15252/msb.20166869
Research output: Contribution to Journal › Article (Published) -
Network of Epistatic Interactions Within a Yeast snoRNA
In:
Science
DOI: https://doi.org/10.1126/science.aaf0965
Research output: Contribution to Journal › Article (Published) -
The PIN domain endonuclease Utp24 cleaves pre-ribosomal RNA at two coupled sites in yeast and humans
In:
Nucleic Acids Research
DOI: https://doi.org/10.1093/nar/gkw213
Research output: Contribution to Journal › Article (Published) -
Loss of the yeast SR protein Npl3 alters gene expression due to transcription readthrough
In:
PLoS Genetics, vol. 11
DOI: https://doi.org/10.1371/journal.pgen.1005735
Research output: Contribution to Journal › Article (Published) -
The human nuclear exosome targeting complex is loaded onto newly synthesized RNA to direct early ribonucleolysis
(15 pages)
In:
Cell Reports, vol. 10, pp. 178-92
DOI: https://doi.org/10.1016/j.celrep.2014.12.026
Research output: Contribution to Journal › Article (Published) -
A pre-ribosomal RNA interaction network involving snoRNAs and the Rok1 helicase
(10 pages)
In:
RNA, vol. 20, pp. 1173-82
DOI: https://doi.org/10.1261/rna.044669.114
Research output: Contribution to Journal › Article (Published) -
Integrity of SRP RNA is ensured by La and the nuclear RNA quality control machinery
(13 pages)
In:
Nucleic Acids Research, vol. 42, pp. 10698-10710
DOI: https://doi.org/10.1093/nar/gku761
Research output: Contribution to Journal › Article (Published) -
Hyb: A bioinformatics pipeline for the analysis of CLASH (crosslinking, ligation and sequencing of hybrids) data
In:
Methods, vol. 65, pp. 263–273
DOI: https://doi.org/10.1016/j.ymeth.2013.10.015
Research output: Contribution to Journal › Article (Published) -
Rate-limiting steps in yeast protein translation
(13 pages)
In:
Cell, vol. 153, pp. 1589-1601
DOI: https://doi.org/10.1016/j.cell.2013.05.049
Research output: Contribution to Journal › Article (Published)