Dr Andy Law
Group Leader/Senior Research Fellow
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Research summary
The development of simple-to-use systems for handling and reformatting data for genetic analyses.
Current research interests
My group works to develop tools and resources for biologists to use in their research exploring the genome and the genetics and genomics of complex traits in farmed and companion animals. Examples of our work include the ArkDBdatabase system and the resSpecies system which hold information pertaining to published genetic linkage maps and provide a means of handling raw experimental data from genetic linkage mapping, QTL mapping and association studies. Websites resSpecies is a web-based system designed to handle data from genetic linkage mapping, quantitative trait locus (QTL) mapping and genetic association studies. It is implemented as a java web application running on top of a postgres database management system. The system is free to use for academics - we provide username/password-based protection of data to restrict access to colaborators and are currently developing the system to provide post-publication access to accession-based data sets in order to simplify the publishing and data-sharing process. You can try out the system for yourself at the resSpecies website-
An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens
In:
Genetics Selection Evolution
DOI: https://doi.org/10.1186/s12711-020-00532-y
Research output: Contribution to Journal › Article (Published) -
Genome-wide CRISPR screen Identifies Host Dependency Factors for Influenza A Virus Infection
In:
Nature Communications, vol. 11
DOI: https://doi.org/10.1038/s41467-019-13965-x
Research output: Contribution to Journal › Article (E-pub ahead of print) -
QTL analysis and genomic selection using RADseq derived markers in Sitka spruce: the potential utility of within family data
In:
Tree Genetics and Genomes, vol. 13
DOI: https://doi.org/10.1007/s11295-017-1118-z
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Rapid identification of bovine MHCI haplotypes in genetically divergent cattle populations Using Next-Generation Sequencing
In:
Immunogenetics, vol. 68, pp. 765-781
DOI: https://doi.org/10.1007/s00251-016-0945-7
Research output: Contribution to Journal › Article (Published) -
Genome-wide association reveals QTL for growth, bone and in vivo carcass traits as assessed by computed tomography in Scottish Blackface lambs
In:
Genetics Selection Evolution, vol. 48
DOI: https://doi.org/10.1186/s12711-016-0191-3
Research output: Contribution to Journal › Article (Published) -
Genetic loci inherited from hens lacking maternal behaviour both inhibit and paradoxically promote this behaviour
In:
Genetics Selection Evolution, vol. 47, pp. 100
DOI: https://doi.org/10.1186/s12711-015-0180-y
Research output: Contribution to Journal › Article (Published) -
A new tool called DISSECT for analyzing large genomic datasets using a Big Data approach
In:
Nature Communications, vol. 6
DOI: https://doi.org/10.1038/ncomms10162
Research output: Contribution to Journal › Article (Published) -
The Roslin Institute - Training Channel
Research output: › Digital or Visual Products (Published) -
Genetic differences at the cholecystokinin A receptor locus result in changes in Agouti related protein expression in the hypothalamus and increased growth rate.
Research output: Contribution to Conference › Abstract (Published) -
Genetic differences at the cholecystokinin A receptor locus result in changes in Agouti related protein expression in the hypothalamus and increased growth rate.
Research output: Contribution to Conference › Abstract (Published)