Dr Andy Law
Group Leader/Senior Research Fellow
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Research summary
The development of simple-to-use systems for handling and reformatting data for genetic analyses.
Current research interests
My group works to develop tools and resources for biologists to use in their research exploring the genome and the genetics and genomics of complex traits in farmed and companion animals. Examples of our work include the ArkDBdatabase system and the resSpecies system which hold information pertaining to published genetic linkage maps and provide a means of handling raw experimental data from genetic linkage mapping, QTL mapping and association studies. Websites resSpecies is a web-based system designed to handle data from genetic linkage mapping, quantitative trait locus (QTL) mapping and genetic association studies. It is implemented as a java web application running on top of a postgres database management system. The system is free to use for academics - we provide username/password-based protection of data to restrict access to colaborators and are currently developing the system to provide post-publication access to accession-based data sets in order to simplify the publishing and data-sharing process. You can try out the system for yourself at the resSpecies website-
Whole genome sequencing identifies multiple loci for critical illness caused by Covid-19
In:
Nature
Research output: Contribution to Journal › Article (Accepted/In press) -
A prenylated dsRNA sensor protects against severe COVID-19
In:
Science
DOI: https://doi.org/10.1126/science.abj3624
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong
In:
Transboundary and Emerging Diseases
DOI: https://doi.org/10.1111/tbed.14304
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Discovery of widespread transcription initiation at microsatellites predictable by sequence-based deep neural network
In:
Nature Communications, vol. 12
DOI: https://doi.org/10.1038/s41467-021-23143-7
Research output: Contribution to Journal › Article (Published) -
Changes in in-hospital mortality in the first wave of COVID-19: a multicentre prospective observational cohort study using the WHO Clinical Characterisation Protocol UK
In:
The Lancet Respiratory Medicine
DOI: https://doi.org/10.1016/S2213-2600(21)00175-2
Research output: Contribution to Journal › Article (Published) -
Dynamic data-driven meta-analysis for prioritisation of host genes implicated in COVID-19
In:
Scientific Reports, vol. 10
DOI: https://doi.org/10.1038/s41598-020-79033-3
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Genetic mechanisms of critical illness in Covid-19
In:
Nature, vol. n/a
DOI: https://doi.org/10.1038/s41586-020-03065-y
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Genetic mechanisms of critical illness in Covid-19
DOI: https://doi.org/10.1101/2020.09.24.20200048
Research output: › Working paper (Published) -
An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens
In:
Genetics Selection Evolution, vol. 52
DOI: https://doi.org/10.1186/s12711-020-00532-y
Research output: Contribution to Journal › Article (Published) -
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection
(18 pages)
In:
Nature Communications, vol. 11
DOI: https://doi.org/10.1038/s41467-019-13965-x
Research output: Contribution to Journal › Article (Published)