Colin Semple Research Group
Medical and Regulatory Genomics
Section: Biomedical Genomics
Research in a Nutshell
The genes embedded in your genome have complex patterns of activity and particular constellations of genes must be active at particular times for biological processes, such as embryonic development, to conclude successfully. I am interested in the fundamental biology of gene regulation: when, how and why genes are turned on and off. We try to understand the mechanisms underlying gene regulation, using computational analyses of genomic datasets. This can provide new insights into human evolution and help us interpret disease processes with aberrant regulation, such as cancers and developmental disorders.
People |
|
|---|---|
| Professor Colin Semple | Group Leader |
| Dr Stuart Aitken | Bioinformatician |
| Dr Jose Campos Parada | IGMM Staff Bioinformatician |
| Dr Philippe Gautier | Bioinformatician |
| Mr Graeme Grimes | Bioinformatician |
| Dr Vera Kaiser | Bioinformatician |
| Dr Alison Meynert | Bioinformatician |
| Dr Tracy Ballinger | Bioinformatician |
| Dr Mihail Halachev | Bioinformatician |
| Dr Ailith Ewing | Bioinformatician |
| Toby Gurran | PhD student |
| Stuart Brown | PhD student |
| Neil Robertson | PhD student |
Contact
Collaborations
- Professor Wendy Bickmore, MRC Human Genetics Unit
- Professor Malcolm Dunlop, MRC Human Genetics Unit
- Professor David Fitzpatrick, MRC Human Genetics Unit
- Professor Chris Haley, MRC Human Genetics Unit
- Professor Martin Taylor, MRC Human Genetics Unit
- Dr Nicola Crosetto, Karolinska Institute, Sweden
- Professor Charlie Gourley, Cancer Research UK Edinburgh Centre
- Professor Piero Carninci, RIKEN Center for Life Science Technologies, Japan
Partners and Funders
Scientific Themes
Medical Genomics, Bioinformatics, Transcriptomics, Epigenomics
Technology Expertise
Computational Biology