Dr Stuart Aitken


Research summary

I am a staff bioinformatician and research scientist in medical and regulatory genomics. Both activities involve the processing and interpretation of next generation sequencing data (RNA Seq, ChIP Seq and HiC) to understand transcriptomic and regulatory processes in model systems and in disease. I am also interested in single cell data, analysis and modelling. In many of these analyses I have applied maximum likelihood, expectation maximisation and Bayesian methods to the problems of fitting models to data, and have have previously studied kinetic modelling in systems biology, parameter optimisation and parameter inference.