Vera Kaiser
Bioinformatician

Contact details
- Tel: 0131 651 8710
- Email: vera.kaiser@igmm.ed.ac.uk
Address
- Street
-
MRC Human Genetics Unit
MRC Institute of Genetics and Molecular Medicine - City
- Post code
- EH4 2XU
Background
Bioinformatician, The University of Edinburgh. Since 2013
Postdoctoral Researcher, The University of California, Berkeley. 2010-2013
Research Scientist, Uppsala University. 2005-2006
Qualifications
PhD, The University of Edinburgh (2009)
B.Sc. in Zoology (1st class), The University of Edinburgh (2005)
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Mutational bias in spermatogonia impacts the anatomy of regulatory sites in the human genome
In:
Genome Research
DOI: https://doi.org/10.1101/gr.275407.121
Research output: Contribution to Journal › Article (Published) -
Pervasive lesion segregation shapes cancer genome evolution
(6 pages)
In:
Nature, vol. 583, pp. 265–270
DOI: https://doi.org/10.1038/s41586-020-2435-1
Research output: Contribution to Journal › Article (Published) -
Chromatin loop anchors are associated with genome instability in cancer and recombination hotspots in the germline
In:
Genome Biology, vol. 19
DOI: https://doi.org/10.1186/s13059-018-1483-4
Research output: Contribution to Journal › Article (Published) -
When TADs go bad: chromatin structure and nuclear organisation in human disease
In:
F1000Research
DOI: https://doi.org/doi:10.12688/f1000research.10792.1
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
Mutational Biases Drive Elevated Rates of Substitution at Regulatory Sites across Cancer Types
(19 pages)
In:
PLoS Genetics, vol. 12
DOI: https://doi.org/10.1371/journal.pgen.1006207
Research output: Contribution to Journal › Article (Published) -
Homozygous loss-of-function variants in European cosmopolitan and isolate populations
In:
Human Molecular Genetics
DOI: https://doi.org/10.1093/hmg/ddv272
Research output: Contribution to Journal › Article (Published) -
De novo transcriptome assembly reveals sex-specific selection acting on evolving neo-sex chromosomes in Drosophila miranda
In:
BMC Genomics, vol. 15, pp. 241
DOI: https://doi.org/10.1186/1471-2164-15-241
Research output: Contribution to Journal › Article (Published) -
The epigenome of evolving Drosophila neo-sex chromosomes: dosage compensation and heterochromatin formation
In:
PLoS Biology, vol. 11, pp. e1001711
DOI: https://doi.org/10.1371/journal.pbio.1001711
Research output: Contribution to Journal › Article (Published) -
Sex-biased gene expression at homomorphic sex chromosomes in emus and its implication for sex chromosome evolution
(6 pages)
In:
Proceedings of the National Academy of Sciences (PNAS), vol. 110, pp. 6453-8
DOI: https://doi.org/10.1073/pnas.1217027110
Research output: Contribution to Journal › Article (Published) -
Conservation and de novo acquisition of dosage compensation on newly evolved sex chromosomes in Drosophila
(6 pages)
In:
Genes and Development, vol. 27, pp. 853-8
DOI: https://doi.org/10.1101/gad.215426.113
Research output: Contribution to Journal › Article (Published) -
A new plant sex-linked gene with high sequence diversity and possible introgression of the X copy
(9 pages)
In:
Heredity, vol. 106, pp. 339-347
DOI: https://doi.org/10.1038/hdy.2010.76
Research output: Contribution to Journal › Article (Published) -
Nonrandom gene loss from the Drosophila miranda neo-Y chromosome
(9 pages)
In:
Genome Biology and Evolution, vol. 3, pp. 1329-37
DOI: https://doi.org/10.1093/gbe/evr103
Research output: Contribution to Journal › Article (Published) -
Nucleotide diversity in Silene latifolia autosomal and sex-linked genes
(8 pages)
In:
Proceedings of the Royal Society B-Biological Sciences, vol. 277, pp. 3283-3290
DOI: https://doi.org/10.1098/rspb.2010.0606
Research output: Contribution to Journal › Article (Published) -
Gene loss on Y chromosomes: a consequence of purifying selection?
(3 pages)
In:
Fly, vol. 4, pp. 270-2
Research output: Contribution to Journal › Article (Published) -
Muller's Ratchet and the Degeneration of the Drosophila miranda Neo-Y Chromosome
(17 pages)
In:
Genetics, vol. 185, pp. 339-348
DOI: https://doi.org/10.1534/genetics.109.112789
Research output: Contribution to Journal › Article (Published) -
Genetic recombination and molecular evolution
(5 pages)
Research output: › Conference contribution (Published) -
Evolution of sex chromosomes in insects
(22 pages)
In:
Annual review of genetics, vol. 44, pp. 91-112
DOI: https://doi.org/10.1146/annurev-genet-102209-163600
Research output: Contribution to Journal › Article (Published) -
Slcyt, a Newly Identified Sex-Linked Gene, Has Recently Moved onto the X Chromosome in Silene latifolia (Caryophyllaceae)
(9 pages)
In:
Molecular Biology and Evolution, vol. 26, pp. 2343-2351
DOI: https://doi.org/10.1093/molbev/msp141
Research output: Contribution to Journal › Article (Published) -
Out of the Andes: patterns of diversification in clearwing butterflies
(14 pages)
In:
Molecular Ecology, vol. 18, pp. 1716-29
DOI: https://doi.org/10.1111/j.1365-294X.2009.04149.x
Research output: Contribution to Journal › Article (Published) -
The effects of deleterious mutations on evolution in non-recombining genomes
(4 pages)
In:
Trends in Genetics, vol. 25, pp. 9-12
DOI: https://doi.org/10.1016/j.tig.2008.10.009
Research output: Contribution to Journal › Article (Published)