Animal Genetic Engineering

Highlighted publications

Articles showcasing our research over the last few years

CRISPR-Based Gene Drives for Pest Control 

Gus R. McFarlane, C. Bruce A. Whitelaw, Simon G. Lillico

CellPress: Trends in Biotechnology, February 2018, volume 36 (2), pp130-133 DOI: 10.1016/j.tibtech.2017.10.001

Pigs lacking the scavenger receptor cysteine-rich domain 5 of CD163 are resistant to PRRSV-1 infection.

Christine Burkard, Tanja Opriessnig, Alan J. Mileham, Tomasz Stadejek, Tahar Ait-Ali, Simon G. Lillico, C. Bruce A. Whitelaw, Alan L. Archibald

Journal of Virology Jun 2018, JVI.00415-18; DOI: 10.1128/JVI.00415-18

Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2gene

Ki-Eun Park, Amy V. Kaucher, Anne Powell, Muhammad Salman Waqas, Shelley E.S. Sandmaier, Melissa J. Oatley, Chi-Hun Park, Ahmed Tibary, David M. Donovan, Le Ann Blomberg, Simon G. Lillico, C. Bruce A. Whitelaw, Alan Mileham, Bhanu P. Telugu, Jon M. Oatley

Scientific Reports volume 7, Article number: 40176 (2017); DOI: 10.1038/srep40176

Mammalian interspecies substitution of immune modulatory alleles by genome editing

Simon G. Lillico, Chris Proudfoot, Tim J. King, Wenfang Tan, Lei Zhang, Rachel Mardjuki, David E. Paschon, Edward J. Rebar, Fyodor D. Urnov, Alan J. Mileham, David G. McLaren, C. Bruce A. Whitelaw

Scientific Reports volume 6, Article number: 21645 (2016); DOI: 10.1038/srep21645

Promotion of alleles by genome editing in livestock breeding programmes

John Hickey, Bruce Whitelaw, Gregor Gorjanc

Journal Animal Breeding Genetics, 133: 83-84; DOI: 10.1111/jbg.12206

Genome edited sheep and cattle

Chris Proudfoot, Daniel F. Carlson, Rachel Huddart, Charles R. Long, Jane H. Pryor, Tim J. King, Simon G. Lillico, Alan J. Mileham, David G. McLaren, C. Bruce A. Whitelaw, Scott C. Fahrenkrug

Transgenic Res (2015) 24: 147 DOI: 10.1007/s11248-014-9832-x