Professor Ross Fitzgerald
Personal Chair of Molecular Bacteriology
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush campus
Midlothian - City
- Post code
- EH25 9RG
Research summary
Use of genomic and molecular tools to examine the evolution and pathogenesis of clinically important species of Staphylococci and Legionella
Current research interests
The laboratory is focused on the evolution and pathogenesis of clinically important species of Staphylococci including the major human and animal pathogen Staphylococcus aureus. We are currently using a range of molecular and genomic tools to understand the evolutionary origin and the molecular basis of staphylococcal diseases. A major goal is to translate our findings into new diagnostic, preventive and therapeutic approaches to controlling infections.-
Multiclonal human origin and global expansion of an endemic bacterial pathogen of livestock: Evolutionary history of bovine Staphylococcus aureus
(11 pages)
In:
Proceedings of the National Academy of Sciences (PNAS), vol. 119, pp. 1-11
DOI: https://doi.org/10.1073/pnas.2211217119
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A graph-based approach for the visualisation and analysis of bacterial pangenomes
(15 pages)
In:
BMC Bioinformatics, vol. 23, pp. 1-15
DOI: https://doi.org/10.1186/s12859-022-04898-2
Research output: Contribution to Journal › Article (Published) -
Epidemiological analysis of Legionnaires’ disease in Scotland: a genomic study
In:
The Lancet Microbe, vol. 3, pp. e835–45
DOI: https://doi.org//10.1016/ S2666-5247(22)00231-2
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Diversity and pathogenesis of Staphylococcus aureus from bovine mastitis: current understanding and future perspectives
In:
BMC Veterinary Research, vol. 18
DOI: https://doi.org/10.1186/s12917-022-03197-5
Research output: Contribution to Journal › Article (Published) -
Population analysis of Legionella pneumophila reveals a basis for resistance to complement-mediated killing
In:
Nature Communications, vol. 12
DOI: https://doi.org/10.1038/s41467-021-27478-z
Research output: Contribution to Journal › Article (Published) -
Evolutionary and functional analysis of coagulase-positivity among the Staphylococci
In:
mSphere
DOI: https://doi.org/10.1128/mSphere.00381-21
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Outcomes of respiratory viral-bacterial co-infection in adult hospitalized patients
In:
EClinicalMedicine, vol. 37
DOI: https://doi.org/10.1016/j.eclinm.2021.100955
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Radical genome remodelling accompanied the emergence of a novel host-restricted bacterial pathogen
In:
PLoS Pathogens, vol. 17
DOI: https://doi.org/10.1371/journal.ppat.1009606
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Staphylococcus aureus secreted lipases do not inhibit innate immune killing mechanisms
In:
Wellcome Open Research , vol. 5, pp. 286
DOI: https://doi.org/10.12688/wellcomeopenres.16194.1
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Advances in transposon mutagenesis of Staphylococcus aureus: insights into pathogenesis and antimicrobial resistance
In:
Trends in Microbiology
DOI: https://doi.org/10.1016/j.tim.2020.11.003
Research output: Contribution to Journal › Article (E-pub ahead of print)