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This job post is for a postdoctoral research associate to conduct research on the role of two G-coupled receptors in the progression of difficult-to-treat acute myeloid leukaemia (AML).
The job holder will need to (i) study the biology of GPR56/GPR97 in leukemic cells (and in normal haematopoietic stem cells as a control), (ii) establish leukaemia cell lines and human iPSCs lacking one or both GPRs, and (iii) study their effects on haematopoietic cell function to identify mechanisms involved in AML progression and chemo-resistance.
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