Kallen Sullivan
Thesis title: Putting a Shell on Oyster Disease: Exploring Genetics and Metabolomics of the Parasite Bonamia to Prevent Pathogen Spread
PhD supervisor:
Address
- Street
-
The Roslin Institute
The University of Edinburgh
Easter Bush Campus - City
- Midlothian
- Post code
- EH25 9RG
Background
I am currently undertaking a PhD in Genetics and Genomics at the Bean Lab, where my research revolves around better understanding Bonamia infections in European flat oysters.
European flat oyster populations have been in decline, largely due to overfishing and disease. There are several initiatives trying to restore native oyster populations around the UK, by transplanting animals from healthy aquaculture sites to sites where they have been historically present. However, when you transplant the oysters, you also run the risk of transplanting pathogens, including micro-cell Haplosporidian parasites in the genus Bonamia. Although there is still a lot to learn about Bonamia, these parasites specifically target and infect the oysters’ immune cells, known as haemocytes, causing significant mortality events in oyster populations.
Over the course of my PhD, I will be using a range of cell culture techniques, -omic approaches and disease challenges models to explore the intricacies of the host-pathogen interface. Ultimately, my goal is to contribute to the successful re-establishment of native oyster populations in the UK.
Qualifications
Aquaculture, parasitology, and marine ecology have always been at the forefront of my interests and professional goals. After receiving a BSc (Hons) in Marine Biology from the University of St. Andrews in 2018, I took on the role of a Research Technologist at the Johns Hopkins University School of Medicine. My focus was on studying the behaviour and ultrastructure of a fish parasite, coupled with developing therapeutics to inhibit its infectivity. Subsequently, I pursued an MSc in Applied Marine and Fisheries Ecology at the University of Aberdeen in 2020, achieving distinction for my thesis on the role of mollusc haemocytes in shell biomineralization and repair. Post-MSc, prior to joining the Aquaculture group at Roslin, I worked at the Woods Hole Oceanographic Institute. There, I managed the zebrafish facility, providing support for toxicology and behaviour research.
[2014 – 2018] BSc (hons), Marine Biology (University of St Andrews)
[2021 – 2022] MSc, Applied Marine and Fisheries Ecology (University of Aberdeen)
[2022 – Present] PhD, Genetics and Genomics (Roslin Institute, University of Edinburgh)
Current project grants
ISP Early Career Grant (2023-2024): Awarded for the project “Oyster Haemocytes: Cellular Diversity or Versatility ”