Dr Helen Brown
Core Scientist (Statisician)
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
Helen Brown is the Senior Statistician at The Roslin Institute. She has an international reputation in the area of mixed models and has published two text books in this area. Previously she has held statistical posts at: University of Edinburgh in Medicine and in the Social Sciences; NHS Quality Improvement Scotland and ISD (NHS); Biomathematics and Statistics Scotland (BIOSS); and at AstraZeneca.
Within her role at The Roslin Institute she is undertaking collaborative scientific research with scientific staff, providing expert statistical advice on methods for research and developing novel statistical approaches to particular problems where appropriate.
Qualifications
2006 Doctor of Science, University of Edinburgh Theory and practice of mixed models applied to medical research
1984 Master of Mathematics, Operational Research, Statistics and Economics, University of Manchester
1999 Master of Informatics, University of Edinburgh Artificial Intelligence
1983 Bachelor of Science, University of York Mathematics
Responsibilities & affiliations
Animal Welfare and Ethics Committee
Research summary
To date my main research interest has been in mixed (or multilevel) models. These involve identifying and accounting for sources of variation and correlation structures in the data and offer potential advantages over conventional modelling methods including: improved efficiency, more appropriate variances and correlations, wider inference and offer the potential to overcome problems caused by missing data.
At The Roslin Institute my research will involve providing the statistical contribution to collaborative scientific research using a range of methods and developing novel statistical approaches to particular problems arising where appropriate. I expect to develop my research in mixed models further in addressing applications arising within the Institute.
-
Investigating volatile semiochemical production from Bos taurus and Bos indicus as a novel phenotype for breeding host resistance to ixodid ticks
(8 pages)
In:
Ticks and tick-borne diseases, vol. 14, pp. 1-8
DOI: https://doi.org/10.1016/j.ttbdis.2023.102200
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Subclinical infection occurs frequently following low dose exposure to prions by blood transfusion
In:
Scientific Reports, vol. 12, pp. 1-11
DOI: https://doi.org/10.1038/s41598-022-15105-w
Research output: Contribution to Journal › Article (Published) -
T2 mapping of cartilage in the equine distal interphalangeal joint with corresponding histology using 0.27 T and 3.0 T MRI
(32 pages)
In:
Equine Veterinary Journal, pp. 1-32
DOI: https://doi.org/10.1111/evj.13900
Research output: Contribution to Journal › Article (E-pub ahead of print) -
In search of a new tool for phenotyping tick resistance in cattle
Research output: Contribution to Conference › Poster (Published) -
Limb development genes underlie variation in human fingerprint patterns
In:
Cell, vol. 185, pp. 95-112.e18
DOI: https://doi.org/10.1016/j.cell.2021.12.008
Research output: Contribution to Journal › Article (Published) -
Real-time monitoring of COVID-19 in Scotland
In:
Journal of the Royal College of Physicians of Edinburgh, vol. 51, pp. S20-S25
DOI: https://doi.org/10.4997/JRCPE.2021.237
Research output: Contribution to Journal › Review article (Published) -
Preclinical transmission of prions by blood transfusion is influenced by donor genotype and route of infection.
In:
PLoS Pathogens, vol. 17
DOI: https://doi.org/10.1371/journal.ppat.1009276
Research output: Contribution to Journal › Article (Published) -
Early partial portal venous contrast enhancement in canine CT-Angiography
In:
Veterinary Radiology & Ultrasound
DOI: https://doi.org/10.1111/vru.12902
Research output: Contribution to Journal › Article (Published) -
Effect of stifle flexion angle on the repeatability of real-time elastosonography of the patellar ligament in medium to large breed dogs
In:
Veterinary and Comparative Orthopaedics and Traumatology
DOI: https://doi.org/10.1055/s-0040-1715493
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Real-Time Monitoring of COVID-19 in Scotland
DOI: https://doi.org/10.1101/2020.07.30.20158790
Research output: › Working paper (Published)