Dr Fergus Doubal
Honorary Senior Lecturer & Consultant Stroke Physician
Research summary
Dementia and some type of strokes are caused by disease of the small blood vessels in the brain but the exact nature of this disease is unknown. We use new scanning techniques of the brain (MRI) and the back of the eye (retinal photography) to work out what happens to these blood vessels to cause dementia and stroke. By doing this we will be able to find new treatments to try to prevent both diseases.
Research aims and interests
- Understanding the pathophysiology of cerebral small vessel disease causing stroke and dementia
- Developing novel markers to predict dementia and stroke
- Developing surrogate markers to use in trials of cerebral small vessel disease
- Using advanced neuroimaging – MRI and retinal photography to delineate the pathophysiology of cerebral small vessel disease
-
Neuropsychiatric symptoms associated with cerebral small vessel disease: a systematic review and meta-analysis
In:
The Lancet Psychiatry
DOI: https://doi.org/10.1016/S2215-0366(20)30431-4
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Predicting specific abilities after disabling stroke: Development and validation of prognostic models
In:
International Journal of Stroke, pp. 1747493020982873
DOI: https://doi.org/10.1177/1747493020982873
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Association of baseline hematoma and edema volumes with one-year outcome and long-term survival after spontaneous intracerebral hemorrhage: A community-based inception cohort study
In:
International Journal of Stroke, pp. 174749302097428
DOI: https://doi.org/10.1177/1747493020974282
Research output: Contribution to Journal › Article (Published) -
Response by Doubal et al to Letter Regarding Article, “Cilostazol for Secondary Prevention of Stroke and Cognitive Decline: Systematic Review and Meta-Analysis”
In:
Stroke, vol. 51
DOI: https://doi.org/10.1161/STROKEAHA.120.032520
Research output: Contribution to Journal › Letter (Published) -
Clinical management of cerebral small vessel disease: a call for a holistic approach
In:
Chinese Medical Journal
DOI: https://doi.org/10.1097/CM9.0000000000001177.
Research output: Contribution to Journal › Article (E-pub ahead of print)