Dr Fergus Doubal

Honorary Senior Lecturer & Consultant Stroke Physician

Research summary

Dementia and some type of strokes are caused by disease of the small blood vessels in the brain but the exact nature of this disease is unknown. We use new scanning techniques of the brain (MRI) and the back of the eye (retinal photography) to work out what happens to these blood vessels to cause dementia and stroke. By doing this we will be able to find new treatments to try to prevent both diseases.

Research aims and interests

  • Understanding the pathophysiology of cerebral small vessel disease causing stroke and dementia
  • Developing novel markers to predict dementia and stroke
  • Developing surrogate markers to use in trials of cerebral small vessel disease
  • Using advanced neuroimaging – MRI and retinal photography to delineate the pathophysiology of cerebral small vessel disease

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