Centre for Clinical Brain Sciences

Brain vascular disease (including stroke)

The multi-disciplinary study of conditions that cause brain vascular injury, such as stroke, is a major focus of CCBS research.

cartoon of an arteriovenous malformation

The Brain Vascular Disease group is a large and internationally recognised team of academic clinicians and researchers. Research spans basic to translational aspects of brain vascular diseases including stroke, and influences clinical guidelines and NHS practice.

 

Edinburgh Stroke Trials header

Edinburgh Stroke Trials is an umbrella organisation that manages academic randomised controlled trials initiated by investigators in Edinburgh, often in collaboration with others. The trials involve researchers and systems developed by the Stroke Research Group, Edinburgh Imaging, and the UKCRC-registered Edinburgh Clinical Trials Unit. Ongoing trials include the Fluoxetine Or Control Under Supervision (FOCUS), REstart or STop Antithrombotics Randomised Trial (RESTART), Prevent-SVD (or LACunar Intervention Trial 1, LACI-1), Start or STop Antithrombotics Randomised Trial (SoSTART), and the LACunar Intervention Trial 2 (LACI-2).

 

Example brain vascular disease projects
Research theme PI
Detection, prevention and treatment of complications after stroke Martin Dennis
Systematic reviews & meta-analyses of animal models Malcolm Macleod
Stroke rehabilitation and prevention of complications Gillian Mead
Research to Understand Stroke due to Haemorrhage (RUSH) Rustam Al-Shahi Salman
Treatment & biomarkers in acute stroke Peter Sandercock
Epidemiology and genetics of stroke and its subtypes Cathie Sudlow
Imaging pathophysiology in acute stroke and cerebral microvascular disease, including Fondation Leducq and Horizon 2020 projects Joanna Wardlaw
Cost effectiveness of imaging in stroke Joanna Wardlaw
Trials and meta-analyses in stroke prognosis and treatment William Whiteley