Dr Dominic Thekkedath Kurian
Proteomics and Metabolomics Facility Mgr
Contact details
Address
- Street
-
The Roslin Institute
Easter Bush Campus
Midlothian - City
- Post code
- EH25 9RG
Background
Dominic manages the Proteomics and Metabolomics core facility of the Roslin Institute, which provides cutting edge analytical services employing advanced mass spectrometry instrumentations for proteomic and metabolomics discoveries.
Dominic has an extensive training in bioanalytical chemistry and mass spectrometry and obtained his Ph.D from University of Calicut, India. After having a few postdoctoral tenures at Indian Agricultural Research Institute, New Delhi, University of Turku, Finland and University of Newcastle, UK, he joined UK’s leading animal research institute, the Institute for Animal Health at Compton, where he ran a biological mass spectrometry facility for three years. Dominic joined the Roslin Institute in 2011.
He is involved with a number of research projects and Institute Strategic Program Grants (ISPGs) where chromatographic and analytical mass spectrometry is utilized. He is currently developing novel mass spectrometry assays for quantifying proteomes and post-translational modifications and targeted analysis of metabolites, which has applications in basic biomedical and clinical research and wildlife forensics.
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Applying genetic technologies to combat infectious diseases in aquaculture
(45 pages)
In:
Aquaculture, pp. 1-45
DOI: https://doi.org/10.1111/raq.12733
Research output: Contribution to Journal › Review article (E-pub ahead of print) -
An optimized comparative proteomic approach as a tool in neurodegenerative disease research.
(26 pages)
In:
Cells, vol. 11, pp. 1 to 26
DOI: https://doi.org/10.3390/cells11172653
Research output: Contribution to Journal › Review article (Published) -
Training associated alterations in equine respiratory immunity using a multiomics comparative approach
In:
Scientific Reports, vol. 12
DOI: https://doi.org/10.1038/s41598-021-04137-3
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Application across species of a one health approach to liquid sample handling for respiratory based -omics analysis
In:
Scientific Reports, vol. 11
DOI: https://doi.org/10.1038/s41598-021-93839-9
Research output: Contribution to Journal › Article (E-pub ahead of print) -
DART Mass spectrometry as a potential tool for the differentiation of captive-bred and wild lion bones.
In:
Biodiversity and Conservation
DOI: https://doi.org/10.1007/s10531-021-02170-2
Research output: Contribution to Journal › Article (Published) -
TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression.
In:
Journal of Hepatology, vol. n/a, pp. 1-72
DOI: https://doi.org/10.1016/j.jhep.2020.11.018
Research output: Contribution to Journal › Article (E-pub ahead of print) -
An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens
In:
Genetics Selection Evolution, vol. 52
DOI: https://doi.org/10.1186/s12711-020-00532-y
Research output: Contribution to Journal › Article (Published) -
Effects of mutations in the effector domain of influenza A virus NS1 protein
In:
BMC Research Notes, vol. 11
DOI: https://doi.org/10.1186/s13104-018-3779-6
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Spermine increases acetylation of tubulins and facilitates autophagic degradation of prion aggregates.
In:
Scientific Reports, vol. 8
DOI: https://doi.org/10.1038/s41598-018-28296-y
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma
In:
Human Mutation: Variation, Informatics and Disease, vol. 38, pp. 942-946
DOI: https://doi.org/10.1002/humu.23246
Research output: Contribution to Journal › Article (Published)