Professor Andrew Jackson (FRS)
Group Leader
- MRC Human Genetics Unit
- Institute of Genetics and Cancer
Contact details
- Email: andrew.jackson@ed.ac.uk
Background
Professor Jackson is a Programme Leader at the MRC Human Genetics Unit, University of Edinburgh. He is also an honorary consultant in Clinical Genetics. He was elected as a fellow of the Royal Society in 2020, as a fellow of the Royal Society of Edinburgh and of the Academy of Medical Sciences in 2014, and as a member of EMBO in 2013. He trained in Medicine in Newcastle, graduating BMedSci in 1990 and MBBS in 1993. His clinical and research postgraduate training was in Newcastle, Leeds and Sheffield, with his PhD undertaken in the laboratory of Prof Geoff Woods on the molecular basis of primary microcephaly.
Over the past 15 years his research has focussed on the identification of genes for inherited neurological disorders and in defining the functional role of the proteins they encode. The Jackson lab has discovered over 20 human disease genes acting in growth and inflammation, all involved in fundamental cellular processes. From a starting point of human disease, his research goal is to provide new insights into basic biological processes.
Qualifications
Education / Academic qualification
Bachelor of Medicine and Bachelor of Surgery, Newcastle University; Bachelor of Science, Newcastle University
Doctor of Philosophy (PhD) 'Molecular Genetics of Primary Microcephaly', University of Leeds
Professional Qualifications
Fellow of the Royal Society; Fellow of Academy of Medical Sciences; Fellow of Royal Society of Edinburgh; Member of European Molecular Biology Organisation; Member of the Royal College of Physicians, MRCP; MB ChB
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cGAS surveillance of micronuclei links genome instability to innate immunity
(5 pages)
In:
Nature, vol. 548, pp. 461–465
DOI: https://doi.org/10.1038/nature23449
Research output: Contribution to Journal › Article (Published) -
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
(9 pages)
In:
Nature, vol. 559, pp. 285–289
DOI: https://doi.org/10.1038/s41586-018-0291-z
Research output: Contribution to Journal › Article (Published) -
Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of polycomb-regulated regions
(10 pages)
In:
Nature Genetics, vol. 51, pp. 96–105
DOI: https://doi.org/10.1038/s41588-018-0274-x
Research output: Contribution to Journal › Article (Published) -
Signatures of TOP1 transcription-associated mutagenesis in cancer and germline
In:
Nature, vol. 602, pp. 623-631
DOI: https://doi.org/10.1038/s41586-022-04403-y
Research output: Contribution to Journal › Article (Published)