Edinburgh Pathology

Prof William Wallace

Honorary Professor

+44 (0)131 242 7134

Department of Pathology

Royal Infirmary of Edinburgh

Edinburgh BioQuarter

51 Little France Crescent

Edinburgh EH16 4SA

Current Research

My research interests focus on lung disease and are rooted in my clinical practice as a diagnostic cardiothoracic pathologist. I have had a long interest in lung injury and remodelling and have well established collaborative links with Professor Sarah Howie in Pathology and the Interstitial Lung Disease Clinic, led by Dr Nik Hirani. More recently I have also been involved on research on molecular aspects of lung cancer, particularly in relation to biomarker expression and the use of modern imaging studies to evaluate vascular cardiac valve disease. I have a major interest in projects evaluating and refining the use of specimens submitted for pathological evaluation to optimise the information that can made available for patient care.

I have also worked closely for a number of years with veterinary colleagues looking at pathological aspects of disease in both animal models and in routine practice.


Dr Nik Hirani University of Edinburgh

Web Links

Full publication list

Selected Publications

WAH Wallace. Respiratory Tract. In ‘Underwood’s Pathology a Clinical Approach’, Ed. SS Cross, Churchill Livingstone, Edinburgh. 7th Edition 2018

WAH Wallace. The pathology of acute lung injury. In ‘Recent Advances in Histopathology 24’ Ed. AM Flanagan JP Medical Ltd, London. 2016

K Donaldson, C Henry and WA Wallace. The role of James Craufurd Gregory and 19th century Scottish physicians and surgeons in the discovery of the link between occupation as a coal miner, black lungs and development of lung disease  J R Coll Physicians Edinb 2017;47:296-302.

CG Stirrat, S Alam, TJ MacGillivray, CD Gray, MR Dweck, J Raftis, WSA Jenkins, WA Wallace,  R Pessotto, KHH Lim, S Mirsadraee,  PA Henriksen, SIR Semple, DE Newby. Ferumoxytol-enhanced magnetic resonance imaging assessing inflammation after myocardial infarction. Heart 2017;103:1528-1535.

DA Dorward, K Walsh, A Oniscu and WA Wallace Molecular pathology of non-small cell lung cancer. Diagnostic Pathology 2017;23:450-457.

CR Lindsay, C Shaw, F Blackhall, FG Blyth, J Brenton, A Chaturvedi, N Clarke, C Dick, TR Evans, G Hall, AM Hanby, DJ Harrison, S Johnston, MD Mason, D Morton, J Newton-Bishop, AG Nicholson, KA Oien, S Popat, D Rassl, R Sharpe, P Taniere, I Walker, WA Wallace, NP West, R Butler, D Gonzales de Castro, M Griffiths and PWM Johnson.  Somatic cancer genetics in the UK: real-world data from phase one of the Cancer Research UK Stratified Medicine Programme ESMO Open 2018; 3:e000408.