Edinburgh Pathology

TMA construction

This service is unavailable at the moment. Contact details and costs for Tissue microarrays (TMAs).

Alex MacLellan   amaclell@staffmail.ed.ac.uk

Pamela Haig       phaig@ed.ac.uk

Sample processing  lothian.CRUKTG@nhs.net

+44 (0)131 651 8011


CRUK Tissue Group

Cancer Research UK Edinburgh Centre

University of Edinburgh

Western General Hospital

Crewe Road South

Edinburgh EH4 2XR

This service is unavailable at the moment

Tissue microarrays (TMAs) consist of a paraffin block containing up to 250 separate tissue cores.  This allows up to 250 different tissue samples to be tested at the same time.

The tissue microarray involves a hollow needle removing a tissue core (normally 0.6mm diameter) from the area of interest on a paraffin embedded tissue block such as tumour samples. These cores are then inserted into a recipient block, in an array pattern, a specific distance apart.  Sections of the TMA block are cut using a microtome, mounted on a microscope slide and analysed using a histological method (most commonly immunohistochemistry or fluorescent in situ hybridization).

The CRUK Tissue Group can make the TMA and help with the collection of blocks, cutting and staining slides (if required) and we can also help marking the area of interest on the slides if a member of staff is trained in the specific tissue type (this is not always possible).  The length of time involved in making a TMA can vary as it depends on how many cores are required, the level of CRUK Tissue Group involvement (i.e if CRUK Tissue Group collect the blocks), and the number of TMA blocks being made.


Retrieval and return of blocks (one case) £30.00 £20.00 £10.00
Subsequent cases £8.00 £6.00 £4.00
Retrieval and return of slides (per case) £30.00 £20.00 £10.00
Unstained sections (up to 10 from same block) £20.00 £15.00 £10.00
Unstained sections (from 10 to  20 from same block) £22.00 £18.00 £8.00
Unstained sections (over 20 from same block) £24.00 £20.00 £10.00
H&E stain only (per slide) £3.00 £2.00 £1.35
TMA construction (per hour) £80.00 £50.00 £25.00
TMA sections (up to 10 from same slide) £80.00 £40.00 £20.00
TMA sections (up to 20 from same slide) £120.00 £60.00 £30.00
TMA sections (up to 30 from same slide) £160.00 £80.00 £40.00
Anonymised data (per case/UB no.) £50.00 £30.00 £20.00
Anonymised data (one off with parameters) £120.00 £80.00 £50.00
Pathologist review per slide £105.00 £80.00 £50.00
Posting slides (per batch) £30.00 £20.00 £10.00