Imaging myocardial infarction
Advanced in vivo imaging is key to cardiac phenotyping as well as for identification of myocardial injury and characterisation of structure, function and molecular processes during remodelling of the heart in disease.
The Gray lab collaborates extensively with Physicists supporting to optimise the use of high frequency ultrasound, magnetic resonance imaging (MRI), positron emission tomography (PET) and optical imaging (fluorescence molecular tomography in vivo for more accurate identification of viable peri-infarct myocardium, as well as structural and functional characterisation in healthy heart and animal models of disease. Optical projection tomography (Figure 1, BHF Image of the Year 2013) allows accurate 3D imaging of infarct size in vitro (Zhao et al., 2015). Projects are available to advance the use of these modalities for in vitro and in vivo imaging.