Keelin Ridge

Thesis title: Determining cerebral small vessel function and flow in small vessel disease

Biography

Background

1st year PhD student at the University of Edinburgh with an interest in medical physics, in particular diagnostic imaging techniques. I am currently working within the Centre for Clinical Brain Sciences using magnetic resonance imaging to understand small vessel disease (SVD). 

Qualifications

MPhys Physics, The University of Durham (2022)

Current research interests

My research involves using magnetic resonance imaging (MRI) techniques to measure vascular impairment in small vessel disease (SVD). In particular, I will be developing metrics to determine the cerebrovascular reactivity (CVR), which indicates the brain's ability to respond to increased demand. These methods will be validated using large, highly-phenotyped datasets and utilised to investigate the linkage between CVR and SVD variables, such as disease severity, common biomarkers and vascular risk factors. This will help better the understanding of SVD pathophysiology and aid patient stratification, paving the way for targeted and effective disease treatment.

Affiliated research centres

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