Dr Michael Thrippleton
Medical Physicist
- Centre for Clinical Brain Sciences
- Edinburgh Imaging
Contact details
- Tel: +44 (0)1315 372663
- Email: m.j.thrippleton@ed.ac.uk
Background
After graduating with a MSci in Natural Sciences, I remained at Cambridge University to complete a PhD in the development of new MR pulse sequences. Following postdoctoral research in solid-state MR at MIT and Glasgow University, I joined the University of Edinburgh in 2008 to work with Professor Hilary Critchley on a clinical trial of MR imaging of patients with uterine fibroids.
Research summary
My research at the Brain Research Imaging Centre is focused on the development and application of advanced MR imaging techniques including:
- Cerebrovascular reactivity imaging
- Magnetic resonance spectroscopy and brain temperature measurement
- Blood brain barrier permeability imaging in ageing and vascular disease
-
Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies
In:
Lancet Neurology
DOI: https://doi.org/10.1016/S1474-4422(19)30197-8
Contribution to journal › Article (E-pub ahead of print) -
Quantifying BBB leakage in small vessel disease: review and consensus recommendations
In:
Alzheimer's & Dementia
DOI: https://doi.org/10.1016/j.jalz.2019.01.013
Contribution to journal › Article (E-pub ahead of print) -
Tolerability, safety and intermediary pharmacological effects of cilostazol and isosorbide mononitrate, alone and combined, in patients with lacunar ischaemic stroke: The LACunar Intervention-1 (LACI-1) trial, a randomised clinical trial
In:
EClinicalMedicine
DOI: https://doi.org/10.1016/j.eclinm.2019.04.001
Contribution to journal › Article (E-pub ahead of print) -
Harmonizing brain magnetic resonance imaging methods for vascular contributions to neurodegeneration
In:
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, vol. 11, pp. 191-204
DOI: https://doi.org/10.1016/j.dadm.2019.01.002
Contribution to journal › Article (E-pub ahead of print) -
MRI Relaxometry for Quantitative Analysis of USPIO Uptake in Cerebral Small Vessel Disease
In:
International Journal of Molecular Sciences, vol. 20, no. 3, pp. 776
DOI: https://doi.org/10.3390/ijms20030776
Contribution to journal › Article (E-pub ahead of print)