Tyler Morrison
Edinburgh Clinical Academic Track (ECAT) Veterinary Clinical Lecturer
- Centre for Inflammation Research
- Royal (Dick) School of Veterinary Studies
Contact details
- Email: tyler.morrison@ed.ac.uk
Background
Tyler graduated a veterinary surgeon from the Royal (Dick) School of Veterinary Studies having intercalated in immunology. During this time he undertook projects in large animal immunology.
Following graduation a period in small animal general practice followed, after which he returned to the university of Edinburgh. As an ECAT-V clinical lecturer he undertook a PhD in inflammation under the supervision of Professors Sarah Walmsley, Shareen Forbes and Moira Whyte and studied the effects of the nutritional microenvironment, and in particular diabetes mellitus, on neutrophil metabolism, function and host injury.
He is currently undertaking a residency in companion animal internal medicine in the R(D)SVS' hospital for small animals whilst continuing his interest in neutrophil biology.
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The emerging role for metabolism in fueling neutrophilic inflammation
In:
Immunological reviews
DOI: https://doi.org/10.1111/imr.13157
Research output: Contribution to Journal › Review article (Published) -
Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence
(53 pages)
DOI: https://doi.org/10.1101/2022.03.11.483935
Research output: › Preprint (Published) -
Neutrophil HIF-1α stabilisation is augmented by mitochondrial ROS produced via the glycerol 3-phosphate shuttle
In:
Blood
DOI: https://doi.org/10.1182/blood.2021011010
Research output: Contribution to Journal › Article (Published) -
A type I IFN, prothrombotic hyperinflammatory neutrophil signature is distinct for COVID-19 ARDS
DOI: https://doi.org/10.12688/wellcomeopenres.16584.2
Research output: › Working paper (E-pub ahead of print) -
Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolism
In:
Journal of Clinical Investigation
DOI: https://doi.org/10.1172/JCI134073
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Neutrophils Fuel Effective Immune Responses through Gluconeogenesis and Glycogenesis
In:
Cell Metabolism, vol. 33, pp. 411-423.e4
DOI: https://doi.org/10.1016/j.cmet.2020.11.016
Research output: Contribution to Journal › Article (Published) -
Semaphorin 3F signaling actively retains neutrophils at sites of inflammation
In:
Journal of Clinical Investigation, vol. 130, pp. 3221-3237
DOI: https://doi.org/10.1172/JCI130834
Research output: Contribution to Journal › Article (Published) -
LEUKOCYTES | Neutrophils
DOI: https://doi.org/10.1016/B978-0-12-801238-3.11695-2
Research output: › Chapter (Published) -
IL4Rα signaling abrogates hypoxic neutrophil survival and limits acute lung injury responses in vivo
(12 pages)
In:
American Journal of Respiratory and Critical Care Medicine, vol. 200, pp. 235–246
DOI: https://doi.org/10.1164/rccm.201808-1599OC
Research output: Contribution to Journal › Article (Published) -
Possible mechanisms of host resistance to Haemonchus contortus infection in sheep breeds native to the Canary Islands
In:
Scientific Reports, vol. 6
DOI: https://doi.org/10.1038/srep26200
Research output: Contribution to Journal › Article (Published)