Sofia Ferreira Gonzalez
Postdoc
Contact details
- Tel: 0131 651 9500
- Email: sofia.ferreira-gonzalez@ed.ac.uk
Address
- Street
-
Centre for Regenerative Medicine
Institute for Regeneration and Repair
The University of Edinburgh
Edinburgh BioQuarter
5 Little France Drive - City
- Edinburgh
- Post code
- EH16 4UU
-
Senolytic treatment preserves biliary regenerative capacity lost through cellular senescence during cold storage
(16 pages)
In:
Science Translational Medicine, vol. 14
DOI: https://doi.org/10.1126/scitranslmed.abj4375
Research output: Contribution to Journal › Article (Published) -
Human biliary epithelial cells from discarded donor livers rescue bile duct structure and function in a mouse model of biliary disease
In:
Cell Stem Cell
DOI: https://doi.org/10.1016/j.stem.2022.02.006
Research output: Contribution to Journal › Article (Published) -
Deletion of kif3a in CK19 positive cells leads to primary cilia loss, biliary cell proliferation and cystic liver lesions in TAA-treated mice
In:
BBA - Molecular Basis of Disease
DOI: https://doi.org/10.1016/j.bbadis.2021.166335
Research output: Contribution to Journal › Article (Published) -
Notch-IGF1 signalling in biliary epithelial cells drives their expansion and inhibits hepatocyte differentiation
In:
Science Signaling
DOI: https://doi.org/10.1126/scisignal.aay9185
Research output: Contribution to Journal › Article (Published) -
Dimethyl fumarate reduces hepatocyte senescence following paracetamol exposure
In:
iScience
DOI: https://doi.org/10.1016/j.isci.2021.102552
Research output: Contribution to Journal › Article (Published) -
Cellular senescence inhibits renal regeneration after injury in mice, with senolytic treatment promoting repair
In:
Science Translational Medicine
DOI: https://doi.org/10.1126/scitranslmed.abb0203
Research output: Contribution to Journal › Article (Published) -
Downregulation of TGR5 (GPBAR1) in biliary epithelial cells contributes to the pathogenesis of sclerosing cholangitis
In:
Journal of Hepatology
DOI: https://doi.org/10.1016/j.jhep.2021.03.029
Research output: Contribution to Journal › Article (Published) -
Cellular Senescence in Liver Disease and Regeneration
(17 pages)
In:
Seminars in liver disease, vol. 41, pp. 50-66
DOI: https://doi.org/10.1055/s-0040-1722262
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Fibroblast Growth Factor 7 Releasing Particles Enhance Islet Engraftment and Improve Metabolic Control Following Islet Transplantation in Mice with Diabetes
In:
American Journal of Transplantation
DOI: https://doi.org/10.1111/ajt.16488
Research output: Contribution to Journal › Article (E-pub ahead of print) -
TWEAK/Fn14 signalling promotes cholangiocarcinoma niche formation and progression.
In:
Journal of Hepatology, vol. n/a, pp. 1-72
DOI: https://doi.org/10.1016/j.jhep.2020.11.018
Research output: Contribution to Journal › Article (E-pub ahead of print) -
TGFβ inhibition restores a regenerative response in acute liver injury by suppressing paracrine senescence
(14 pages)
In:
Science Translational Medicine, vol. 10
DOI: https://doi.org/10.1126/scitranslmed.aan1230
Research output: Contribution to Journal › Article (Published) -
Paracrine cellular senescence exacerbates biliary injury and impairs regeneration
In:
Nature Communications, vol. 9
DOI: https://doi.org/10.1038/s41467-018-03299-5
Research output: Contribution to Journal › Article (Published) -
The STAT3-IL10-IL6 pathway is a novel regulator of macrophage efferocytosis and phenotypic conversion in sterile liver injury
In:
The Journal of Immunology, vol. 200, pp. 1169-1187
DOI: https://doi.org/10.4049/jimmunol.1701247
Research output: Contribution to Journal › Article (Published) -
Cholangiocytes act as Facultative Liver Stem Cells during Impaired Hepatocyte Regeneration
(5 pages)
In:
Nature, vol. 547, pp. 350–354
DOI: https://doi.org/10.1038/nature23015
Research output: Contribution to Journal › Article (Published) -
Notch3 drives development and progression of cholangiocarcinoma
(6 pages)
In:
Proceedings of the National Academy of Sciences (PNAS), vol. 113, pp. 12250-12255
DOI: https://doi.org/10.1073/pnas.1600067113
Research output: Contribution to Journal › Article (Published)