Matthew Bailey (BSc (Hons.), PhD)
Personal Chair of Renal Physiology
Address
- Street
-
Centre for Cardiovascular Science,
The Queen's Medical Research Institute,
Edinburgh BioQuarter,
47 Little France Crescent - City
- Edinburgh
- Post code
- EH16 4TJ
Research summary
Matt Bailey is a renal physiologist with training from UCL, CNRS and Yale University. Currently Chair of Renal Physiology at Edinburgh, he investigates physiological and molecular pathways of cardiovascular and renal dysfunction in hypertension and renal disease. Bailey’s research group has longstanding expertise in using innovative methodologies to assessment of hypertension and renal dysfunction in mice, including measurement of vascular and tubular function in vivo and ex vivo. He has published 75 papers (H-index of 28), including recent papers in JASN (x2); Hypertension (x3), Kidney International (x2), eBioMedicine and Circulation. Awarded >£2.5M in research funding and >£7.5M for Doctoral Training, he has current grants from Kidney Research UK, British Heart Foundation and Diabetes UK. Matt writes for major renal textbooks (The Kidney, The Oxford Textbook of Clinical Nephrology, Comprehensive Clinical Nephrology) and teaches at renal summer schools across Europe. He is active in public engagement (www.youtube.com/watch?v=cZEmj_lks-o) and is shortlisted for THE2018 Outstanding Research Supervisor of the Year. His current main project areas are: 1) the control of renal haemodynamics and tubular function by intrarenal signalling systems, such as ATP, endothelin and lactate; and 2) the mechanisms contributing to salt-sensitive hypertension.
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Oral Potassium Supplementation Flicks the Renal K-Switch in Humans
In:
Kidney International Reports
DOI: https://doi.org/10.1016/j.ekir.2023.04.013
Research output: Contribution to Journal › Editorial (E-pub ahead of print) -
Sodium–glucose cotransporter 2 inhibition does not improve the acute pressure natriuresis response in rats with type 1 diabetes
(10 pages)
In:
Experimental physiology, vol. 10, pp. 480-490
DOI: https://doi.org/10.1113/EP090849
Research output: Contribution to Journal › Article (Published) -
Sodium-glucose co-transporter 2 inhibition does not improve the acute pressure natriuresis response in rats with Type 1 diabetes
(10 pages)
In:
Experimental Psychology, vol. 108, pp. 480-490
DOI: https://doi.org/10.1113/EP090849
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Kidney function and cognitive impairment
In:
Experimental physiology
DOI: https://doi.org/10.1113/EP091003
Research output: Contribution to Journal › Editorial (E-pub ahead of print) -
Endothelin blockade prevents the long-term cardiovascular & renal sequelae of acute kidney injury
In:
Science Translational Medicine
DOI: https://doi.org/10.1126/scitranslmed.abf5074
Research output: Contribution to Journal › Article (Published) -
High salt intake activates the hypothalamic-pituitary-adrenal axis, amplifies the stress response, and alters tissue glucocorticoid exposure in mice
In:
Cardiovascular Research
DOI: https://doi.org/10.1093/cvr/cvac160
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Mapping the Transcriptome Underpinning Acute Corticosteroid Action within the Cortical Collecting Duct
In:
Kidney360
DOI: https://doi.org/10.34067/KID.0003582022
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Arterial stiffness, endothelial dysfunction and impaired fibrinolysis are pathogenic mechanisms contributing to cardiovascular risk in ANCA-associated vasculitis
(12 pages)
In:
Kidney International, vol. 102, pp. 1115-1126
DOI: https://doi.org/10.1016/j.kint.2022.07.026
Research output: Contribution to Journal › Article (Published) -
Pressure natriuresis induced alterations in renal sodium transporters in diabetic and non-diabetic rats
Research output: Contribution to Conference › Poster (Published) -
Sex Difference in Renal Artery Contractility in a Novel CRISPR/Cas9-Generated P2X7 Knockout Rat
(1 page)
In:
The FASEB Journal, vol. 36
DOI: https://doi.org/10.1096/fasebj.2022.36.S1.R5740
Research output: Contribution to Journal › Meeting abstract (Published) -
The impact of excessive salt intake on human health
In:
Nature Reviews Nephrology, vol. 18, pp. 321-335
DOI: https://doi.org/10.1038/s41581-021-00533-0
Research output: Contribution to Journal › Article (Published) -
The acute pressure natriuresis response is suppressed by selective ETA receptor blockade
In:
Clinical science
DOI: https://doi.org/10.1042/CS20210937
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Editorial for the “The Tribute of Physiology for the Understanding of COVID-19 Disease” collection
In:
Frontiers in physiology
DOI: https://doi.org/10.3389/fphys.2021.761644
Research output: Contribution to Journal › Editorial (Published) -
The UK experience of stereoelectroencephalography in children: An analysis of factors predicting the identification of a seizure-onset zone and subsequent seizure freedom
(14 pages)
In:
Epilepsia, vol. 62, pp. 1883-1896
DOI: https://doi.org/10.1111/epi.16954
Research output: Contribution to Journal › Article (Published) -
Salbutamol and salt-sensitive hypertension
In:
Kidney International
DOI: https://doi.org/10.1016/j.kint.2021.05.023
Research output: Contribution to Journal › Comment/debate (Published) -
Sodium-glucose co-transporter 2 inhibition does not alter the pressure natriuretic response in Sprague Dawley rats.
Research output: Contribution to Conference › Abstract (Published) -
Sodium-glucose co-transporter 2 inhibition does not alter the pressure natriuretic response in Sprague Dawley rats
Research output: Contribution to Conference › Abstract (Published) -
Circulating argonaute-bound microRNA-126 reports vascular dysfunction and treatment response in acute and chronic kidney disease
In:
iScience
DOI: https://doi.org/10.1016/j.isci.2020.101937
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Non-dipping Blood Pressure:predictive or reactive renal sodium handling failure
In:
Physiology
DOI: https://doi.org/10.1152/physiol.00024.2020
Research output: Contribution to Journal › Article (Published) -
Purinergic signalling in the kidney: In physiology and disease
In:
Biochemical Pharmacology
DOI: https://doi.org/10.1016/j.bcp.2020.114389
Research output: Contribution to Journal › Article (E-pub ahead of print)