Matthew Bailey (BSc (Hons.), PhD)
Personal Chair of Renal Physiology
Address
- Street
-
Centre for Cardiovascular Science,
The Queen's Medical Research Institute,
Edinburgh BioQuarter,
47 Little France Crescent - City
- Edinburgh
- Post code
- EH16 4TJ
Research summary
Matt Bailey is a renal physiologist with training from UCL, CNRS and Yale University. Currently Chair of Renal Physiology at Edinburgh, he investigates physiological and molecular pathways of cardiovascular and renal dysfunction in hypertension and renal disease. Bailey’s research group has longstanding expertise in using innovative methodologies to assessment of hypertension and renal dysfunction in mice, including measurement of vascular and tubular function in vivo and ex vivo. He has published 75 papers (H-index of 28), including recent papers in JASN (x2); Hypertension (x3), Kidney International (x2), eBioMedicine and Circulation. Awarded >£2.5M in research funding and >£7.5M for Doctoral Training, he has current grants from Kidney Research UK, British Heart Foundation and Diabetes UK. Matt writes for major renal textbooks (The Kidney, The Oxford Textbook of Clinical Nephrology, Comprehensive Clinical Nephrology) and teaches at renal summer schools across Europe. He is active in public engagement (www.youtube.com/watch?v=cZEmj_lks-o) and is shortlisted for THE2018 Outstanding Research Supervisor of the Year. His current main project areas are: 1) the control of renal haemodynamics and tubular function by intrarenal signalling systems, such as ATP, endothelin and lactate; and 2) the mechanisms contributing to salt-sensitive hypertension.
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The acute pressure natriuresis response is suppressed by selective ETA receptor blockade
In:
Clinical science
DOI: https://doi.org/10.1042/CS20210937
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Salt and disease
In:
Nature Reviews Nephrology
Research output: Contribution to Journal › Article (Accepted/In press) -
Editorial for the “The Tribute of Physiology for the Understanding of COVID-19 Disease” collection
In:
Frontiers in physiology
DOI: https://doi.org/10.3389/fphys.2021.761644
Research output: Contribution to Journal › Editorial (Published) -
Salbutamol and salt-sensitive hypertension
In:
Kidney International
DOI: https://doi.org/10.1016/j.kint.2021.05.023
Research output: Contribution to Journal › Comment/debate (Published) -
Sodium-glucose co-transporter 2 inhibition does not alter the pressure natriuretic response in Sprague Dawley rats
Research output: Contribution to Conference › Abstract (Published) -
Circulating argonaute-bound microRNA-126 reports vascular dysfunction and treatment response in acute and chronic kidney disease
In:
iScience
DOI: https://doi.org/10.1016/j.isci.2020.101937
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Non-dipping Blood Pressure:predictive or reactive renal sodium handling failure
In:
Physiology
DOI: https://doi.org/10.1152/physiol.00024.2020
Research output: Contribution to Journal › Article (Published) -
Purinergic signalling in the kidney: In physiology and disease
In:
Biochemical Pharmacology
DOI: https://doi.org/10.1016/j.bcp.2020.114389
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Transfer of hepatocellular microRNA regulates cytochrome P450 2E1 in renal tubular cells
In:
EBioMedicine, vol. 62
DOI: https://doi.org/10.1016/j.ebiom.2020.103092
Research output: Contribution to Journal › Article (Published) -
Biological context linking hypertension and higher risk for COVID-19 severity
In:
Frontiers in physiology
DOI: https://doi.org/10.3389/fphys.2020.599729
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Activation of the sympathetic nervous system promotes blood pressure salt-sensitivity in C57BL6/J mice
In:
Hypertension
DOI: https://doi.org/10.1161/hypertensionaha.120.16186
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Endogenous activation of GLP-1 receptor contributes to blood pressure control: role of proximal tubule NHE3, renal angiotensin II and insulin sensitivity
In:
Hypertension
DOI: https://doi.org/10.1161/HYPERTENSIONAHA.120.14868
Research output: Contribution to Journal › Article (Published) -
Deletion of the myeloid endothelin-B receptor confers long-term protection from angiotensin II-mediated renal, retinal & vascular injury
In:
Kidney International
DOI: https://doi.org/10.1016/j.kint.2020.05.042
Research output: Contribution to Journal › Article (Published) -
Endothelin-1 mediates the systemic and renal hemodynamic effects of GPR81 activation
In:
Hypertension
DOI: https://doi.org/10.1161/HYPERTENSIONAHA.119.14308
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Salt‐sensitive hypertension and the immune system
In:
Experimental physiology
DOI: https://doi.org/10.1113/EP088533
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Hyperkalemia: pathophysiology, risk factors and consequences
In:
Nephrology dialysis transplantation, vol. 34, pp. iii2-iii11
DOI: https://doi.org/10.1093/ndt/gfz206
Research output: Contribution to Journal › Review article (Published) -
Glucocorticoid receptor activation stimulates the Na-Cl co-transporter and influences the diurnal rhythm of its phosphorylation
In:
American Journal of Physiology - Renal Physiology, vol. 317, pp. F1536-F1548
DOI: https://doi.org/10.1152/ajprenal.00372.2019
Research output: Contribution to Journal › Article (Published) -
Refining the Mouse Subtotal Nephrectomy in Male 129S2/SV Mice for Consistent Modeling of Progressive Kidney Disease With Renal Inflammation and Cardiac Dysfunction
In:
Frontiers in physiology, vol. 10
DOI: https://doi.org/10.3389/fphys.2019.01365
Research output: Contribution to Journal › Article (Published) -
Trichostatin A Blocks Aldosterone-Induced Na+ Transport And Control Of Serum- And Glucocorticoid-Inducible Kinase 1 In Cortical Collecting Duct Cells
In:
British Journal of Pharmacology
DOI: https://doi.org/10.1111/bph.14837
Research output: Contribution to Journal › Article (E-pub ahead of print) -
A novel role for myeloid endothelin-B receptors in hypertension
(17 pages)
In:
European Heart Journal, vol. 40, pp. 768-784
DOI: https://doi.org/10.1093/eurheartj/ehy881
Research output: Contribution to Journal › Article (Published)