Mark Miller (BSc, PhD)
Senior Research Fellow
Address
- Street
-
Centre for Cardiovascular Science,
The Queen's Medical Research Institute,
Edinburgh BioQuarter,
47 Little France Crescent - City
- Edinburgh
- Post code
- EH16 4TJ
Research summary
My research investigates the cardiovascular effects of air pollution, which are believed to be responsible for killing millions of people worldwide every year. I specialise in the biological mechanisms by which inhaled nanoparticles lead to detrimental effects on multiple aspects of the cardiovascular system. This work also encompasses engineered nanoparticles, the manufacture of which is increasing on an exponential scale for a diverse range of applications. These nanoparticles share many of the physicochemical properties with environmental particles, yet their potential to cause cardiovascular harm has received very little attention. I also have an interest in atherosclerosis, the vascular endothelium, nitric oxide and oxidative stress. Our group specialises in in vitro and in vivo models of vascular function, with immediate translational links to clinical research and public health.