Dr Martin Reijns (BSc Biotechnology, MSc Cell and Molecular Biology, PhD Molecular Genetics)
Research Fellow
- MRC Human Genetics Unit
- MRC Institute of Genetics and Molecular Medicine
Contact details
- Tel: +44(0)131 651 8633
- Email: martin.reijns@ed.ac.uk
Address
- Street
-
Western General Hospital
Crewe Road - City
- Edinburgh
- Post code
- EH4 2XU
Background
Martin Reijns received his BSc degree in Biotechnology from Wageningen University in the Netherlands, and specialised in Cell & Molecular Biology (MSc). He moved to Scotland in 2002, where he worked for one year as a research assistant in Molecular Genetics working on bacterial site-specific recombination (Colloms lab, Glasgow University) before starting his PhD in Molecular Genetics, working on RNA splicing and turnover in budding yeast (Beggs lab, The University of Edinburgh). After completion of his PhD in 2006, he worked as a postdoctoral researcher in the Beggs lab for another 10 months. In 2007 he started a career development fellowship in the lab of Prof Andrew Jackson at the MRC Human Genetics Unit, and was promoted to Research Fellow in 2012.
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User acceptability of saliva and gargle samples for identifying COVID-19 positive high-risk workers and household contacts
In:
Diagnostic microbiology and infectious disease, vol. 104
DOI: https://doi.org/10.1016/j.diagmicrobio.2022.115732
Research output: Contribution to Journal › Article (Published) -
DNA damage contributes to neurotoxic inflammation in Aicardi-Goutières Syndrome astrocytes
In:
Journal of Experimental Medicine
DOI: https://doi.org/10.1084/jem.20211121
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Signatures of TOP1 transcription-associated mutagenesis in cancer and germline
In:
Nature, vol. 602, pp. 623-631
DOI: https://doi.org/10.1038/s41586-022-04403-y
Research output: Contribution to Journal › Article (Published) -
User acceptability of saliva and gargle samples for identifying COVID-19 positive high-risk workers
DOI: https://doi.org/10.1101/2022.01.28.22270033
Research output: › Preprint (Published) -
Novel Escherichia coli active site dnaE alleles with altered base and sugar selectivity
In:
Molecular Microbiology
DOI: https://doi.org/10.1111/mmi.14779
Research output: Contribution to Journal › Article (E-pub ahead of print) -
cGAS-mediated induction of type I interferon due to inborn errors of histone pre-mRNA processing
(9 pages)
In:
Nature Genetics, vol. 52, pp. 1364-1372
DOI: https://doi.org/10.1038/s41588-020-00737-3
Research output: Contribution to Journal › Article (Published) -
A sensitive and affordable multiplex RT-qPCR assay for SARS-CoV-2 detection
In:
PLoS Biology, vol. 18, pp. e3001030
DOI: https://doi.org/10.1371/journal.pbio.3001030
Research output: Contribution to Journal › Article (E-pub ahead of print) -
PRIM1 Deficiency Causes a Distinctive Primordial Dwarfism Syndrome
(14 pages)
In:
Genes and Development, vol. 34, pp. 1520-1533
DOI: https://doi.org/10.1101/gad.340190.120
Research output: Contribution to Journal › Article (Published) -
Biallelic variants in DNA2 cause microcephalic primordial dwarfism
In:
Human Mutation: Variation, Informatics and Disease, vol. 40, pp. 1063-1070
DOI: https://doi.org/10.1002/humu.23776
Research output: Contribution to Journal › Article (Published) -
CRISPR screens identify genomic ribonucleotides as a source of PARP-trapping lesions
(9 pages)
In:
Nature, vol. 559, pp. 285–289
DOI: https://doi.org/10.1038/s41586-018-0291-z
Research output: Contribution to Journal › Article (Published) -
Gain of function DNMT3A mutations cause microcephalic dwarfism and hypermethylation of polycomb-regulated regions
(10 pages)
In:
Nature Genetics, vol. 51, pp. 96–105
DOI: https://doi.org/10.1038/s41588-018-0274-x
Research output: Contribution to Journal › Article (Published) -
Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in Mice
In:
Gastroenterology
DOI: https://doi.org/10.1053/j.gastro.2018.09.047
Research output: Contribution to Journal › Article (Published) -
DNA Polymerase epsilon deficiency causes IMAGe Syndrome with variable immunodeficiency
In:
American Journal of Human Genetics, vol. 103, pp. 1038-1044
DOI: https://doi.org/10.1016/j.ajhg.2018.10.024
Research output: Contribution to Journal › Article (Published) -
Ribonucleotide excision repair is essential to prevent squamous cell carcinoma of the skin
In:
Cancer Research
DOI: https://doi.org/10.1158/0008-5472.CAN-18-1099
Research output: Contribution to Journal › Article (Published) -
RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition
(22 pages)
In:
EMBO Journal, vol. 37
DOI: https://doi.org/10.15252/embj.201798506
Research output: Contribution to Journal › Article (Published) -
Rare ADAR and RNASEH2B variants and a type I interferon signature in glioma and prostate carcinoma risk and tumorigenesis
(18 pages)
In:
Acta Neuropathologica, vol. 134, pp. 905-922
DOI: https://doi.org/10.1007/s00401-017-1774-y
Research output: Contribution to Journal › Article (Published) -
Aberrant ribonucleotide incorporation and multiple deletions in mitochondrial DNA of the murine MPV17 disease model
In:
Nucleic Acids Research
DOI: https://doi.org/10.1093/nar/gkx1009
Research output: Contribution to Journal › Article (Published) -
cGAS surveillance of micronuclei links genome instability to innate immunity
(5 pages)
In:
Nature, vol. 548, pp. 461–465
DOI: https://doi.org/10.1038/nature23449
Research output: Contribution to Journal › Article (Published) -
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism
(13 pages)
In:
Nature Genetics, vol. 49, pp. 537–549
DOI: https://doi.org/10.1038/ng.3790
Research output: Contribution to Journal › Article (Published) -
Ribonuclease H2 mutations induce a cGAS/STING-dependent innate immune response
(14 pages)
In:
EMBO Journal, vol. 35, pp. 831-844
DOI: https://doi.org/10.15252/embj.201593339
Research output: Contribution to Journal › Article (Published)