Dr Jennifer Regan
Lecturer in Immunology
- Institute of Immunology and Infection
Contact details
- Tel: 0131 6513630
- Email: Jenny.Regan@ed.ac.uk
- ResearchGate profile
Address
- Street
-
Institute of Immunology & Infection Research
Ashworth Laboratories Room 1.11
Charlotte Auerbach Road - City
- Edinburgh
- Post code
- EH9 3FL
Background
2017 Visiting Postdoctoral Scientist, Max Planck Institute for Biology of Ageing, Cologne, Germany
2012 Postdoctoral Research Fellow, Institute for Healthy Ageing, University College London, UK
2008 EMBO Postdoctoral Research Fellow, Instituto de Medicina Molecular, Lisbon, Portugal
2002 PhD in Developmental Neurobiology, University College London, UK
Qualifications
2008 PhD Developmental Neurobiology, University College London
Research summary
Women have stronger immune responses than do men to most infections, but suffer from greater levels of autoimmunity, and this sex difference is apparent throughout the animal kingdom. We use live imaging and the elegant genetics possible in Drosophila to understand how dynamic behaviors of immune cells differ between sexes, and how these affect the response to infection, inflammation, ageing and survival.
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Sexual identity of enterocytes regulates autophagy to determine intestinal health, lifespan and responses to rapamycin
(14 pages)
In:
Nature Aging, vol. 2, pp. 1145-1158
DOI: https://doi.org/10.1038/s43587-022-00308-7
Research output: Contribution to Journal › Article (Published) -
Fly immunity comes of age: The utility of Drosophila as a model for studying variation in immunosenescence.
In:
Frontiers in aging, vol. 3
DOI: https://doi.org/10.3389/fragi.2022.1016962
Research output: Contribution to Journal › Article (Published) -
Long-lasting geroprotection from brief rapamycin treatment in early adulthood by persistently increased intestinal autophagy
(13 pages)
In:
Nature Aging, vol. 2, pp. 824-836
DOI: https://doi.org/10.1038/s43587-022-00278-w
Research output: Contribution to Journal › Article (Published) -
Lifespan extension via dietary restriction: Time to reconsider the evolutionary mechanisms?
In:
BioEssays
DOI: https://doi.org/10.1002/bies.201900241
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Sexual Dimorphisms in Innate Immunity and Responses to Infection in Drosophila melanogaster
In:
Frontiers in Immunology, vol. 10
DOI: https://doi.org/10.3389/fimmu.2019.03075
Research output: Contribution to Journal › Article (Published) -
Dietary restriction and insulin‐like signalling pathways as adaptive plasticity: A synthesis and re‐evaluation
In:
Functional Ecology, vol. 34
DOI: https://doi.org/10.1111/1365-2435.13418
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Intestinal fork head regulates nutrient absorption and promotes longevity
(12 pages)
In:
Cell Reports, vol. 21, pp. 641-653
DOI: https://doi.org/10.1016/j.celrep.2017.09.042
Research output: Contribution to Journal › Article (Published)