Dr Donald MacIntyre
NRS Clinician and Honorary Reader

- Centre for Clinical Brain Sciences, Division of Psychiatry
- NHS Lothian
Contact details
- Email: d.macintyre@ed.ac.uk
Background
Donald is an NHS consultant general psychiatrist, currently seconded to NHS 24 as mental health clinical lead, a post which he combines with clinical research. He graduated in Edinburgh in 1996, worked in London as a casualty officer, and started psychiatric training in 1999. He has combined research and clinical practice throughout his career. He was fortunate to be involved in the family and population-based biobank, Generation Scotland, and its extension, STRADL, led by Prof Andrew McIntosh.
Donald was awarded MD in 2013, an NHS Research Scotland (NRS) Fellowship in 2014 and was promoted to Honorary Reader in 2017.
Responsibilities & affiliations
- Associate member of the Centre for Cognitive Ageing and Cognitive Epidemiology
- Advisor to the MRC Sudden Death Brain Bank
Research summary
Donald is interested in exploring the validity of psychiatric diagnoses using novel methods of phenotyping and using technological innovations, routine measurement and record linkage to improve mental health care and treatment.
Funding Sources
- Chief Scientist Office
- Digital Health Institute
- Scottish Mental Health Research Network
- Scottish Government
-
A loss of mature microglial markers without immune activation in schizophrenia
In:
Glia
DOI: https://doi.org/10.1002/glia.23962
Research output: Contribution to Journal › Article (Published) -
The Genetics of the Mood Disorder Spectrum: Genome-wide Association Analyses of More Than 185,000 Cases and 439,000 Controls
In:
Biological Psychiatry
DOI: https://doi.org/10.1016/j.biopsych.2019.10.015
Research output: Contribution to Journal › Article (Accepted/In press) -
Cohort profile for the STratifying Resilience and Depression Longitudinally (STRADL) study: A depression-focused investigation of Generation Scotland, using detailed clinical, cognitive, and neuroimaging assessments
In:
Wellcome Open Research , vol. 4, pp. 185
DOI: https://doi.org/10.12688/wellcomeopenres.15538.1
Research output: Contribution to Journal › Article (Published) -
Increased number of T-lymphocytes in post-mortem brain tissue of patients with schizophrenia.
In:
Schizophrenia Research
DOI: https://doi.org/10.1016/j.schres.2019.10.032
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns
In:
Nature Communications, vol. 10
DOI: https://doi.org/10.1038/s41467-019-10461-0
Research output: Contribution to Journal › Article (Published)