W. David Hill

Statistical Geneticist

  • Psychology
  • School of Philosophy, Psychology and Language Sciences

Contact details



Room F1, Psychology Building

7 George Square, Edinburgh
Post code



Hill, W. D. (2018). A Further Comment on ‘Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets’ by Lam et al. Twin Research and Human Genetics, doi: https://doi.org/10.1017/thg.2018.55.


Anderson, E. L., Howe, L. D., Wade, K. H., Ben-Shlomo, Y., Hill, W. D., Deary, I. J., … & Hemani, G. (2018). Education, intelligence and Alzheimer's disease: Evidence from a multivariable two-sample Mendelian randomization study. bioRxiv. doi: https://doi.org/10.1101/401042.


Srinivasan, S., Bettella, F., Frei, O,. Hill, W. D., Wang, Y., Witoelar, A., … & Andreassen, O. A. (2018). Enrichment of genetic markers of recent human evolution in educational and cognitive traits. Scientific Reports, 8(1), 12585.


Hill, W. D., Harris, S. E., Deary, I. J. (2018). What genome-wide association studies reveal about the association between intelligence and mental health. Current Opinion in Psychology.


Deary, I. J., Harris, S. E., Hill, W. D. (2018). What genome-wide association studies reveal about the association between intelligence and physical health, illness, and mortality. Current Opinion in Psychology.


Davies, G., Lam, M., Harris, S. E., Trampush, J. W., Luciano, M., Hill, W. D., … Deary I. J. (2018). Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function. Nature Communications. doi:10.1038/s41467-018-04362-x


Hill, W. D. (2018). Comment on ‘Large-Scale Cognitive GWAS Meta-Analysis Reveals Tissue-Specific Neural Expression and Potential Nootropic Drug Targets’ by Lam et al. Twin Research and Human Genetics, 21(2), 84-88.


Hill, W. D., Marioni, R, Maghzian, O., Ritchie, S., Hagenaars, S., Mcintosh, A. M., Davies, G., Gale, C. R., & Deary I. J. (2018). A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence. Molecular Psychiatry. doi:10.1038/s41380-017-0001-5


Hill, W. D., Arslan, R. C., Xia, C., Luciano, M., Amador, C., Navarro, P., Hayward, C., Nagy, N., Porteous, D., McIntosh, A.M., Deary, I. J., Haley, C.S., & Penke, L. (2018). Genomic analysis of family data reveals additional genetic effects on intelligence and personality. Molecular Psychiatry. doi:10.1038/s41380-017-0005-1.


Luciano, M., Hagenaars, S. P., Davies, G., Hill, W. D., Clarke, T. K., Shirali, M., ... & Deary I. J. (2018). Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism. Nature genetics, 50(1), 6.


Hill, W.D., Weiss, A., McIntosh, A. M., Gale, C. R., Deary, I. J. (2017). Genetic contribution to two factors of neuroticism is associated with affluence, better health, and longer life. bioRxiv. doi:10.1101/146787


Fernández, E., Collins, M. O., Frank, R. A., Zhu, F., Kopanitsa, M. V., Nithianantharajah, J., 7 authors, Hill, W.D., ... & Grant, S.G.N. (2017). Arc Requires PSD95 for Assembly into Postsynaptic Complexes Involved with Neural Dysfunction and Intelligence. Cell reports, 21(3), 679-691.


Smeland, O. B., Frei, O., Kauppi, K., Hill, W. D., Li, W., Wang, Y., ... & Andreassen, O. A. (2017). Identification of genetic loci jointly influencing schizophrenia risk and the cognitive traits of verbal-numerical reasoning, reaction time, and general cognitive function. JAMA psychiatry, 74(10), 1065-1075.


Luciano, M., Hagenaars, S. P., Cox, S. R., Hill, W. D., Davies, G., Harris, S. E., ... & Bates, T. C. (2017). Single Nucleotide Polymorphisms Associated with Reading Ability Show Connection to Socio-Economic Outcomes. Behavior Genetics, 47(5), 469-479.


Hagenaars, S. P., Hill, W.D., Harris, S.E., Ritchie, S.J., Davies, G., Liewald, D.C., Gale, C. R., Porteous, D.J., Deary, I.J., Marrioni, R.E. (2017). Genetic prediction of male pattern baldness. PLoS Genetics, 13(2), e1006594.


Hagenaars, S. P., Cox, S. R., Hill, W. D., Davies, G., Liewald, D. C., Harris, S. E., ... & CHARGE consortium Cognitive Working Group. (2017). Genetic contributions to trail making test performance in UK Biobank. Molecular psychiatry. doi:10.1038/mp.2017.189.


Deary, V., Hagenaars, S. P., Harris, S. E., Hill, W. D., Davies, G., Liewald, D. C., ... & Deary, I.J. (2017). Genetic contributions to self-reported tiredness. Molecular psychiatry, 23(3), 609.


Hill, W.D., Davies, G., Harris, S.E., Hagenaars, S.P., Liewald, D., Penke, L. Gale. C.R. & Deary, I.J. (2016). Molecular genetic aetiology of general cognitive function is enriched in evolutionarily conserved regions. Translational Psychiatry, 6(12), e980.


Hill, W.D., Hagenaars, S.P., Marioni, R.E., Harris, S.E., Liewald, D.C., Davies, G., International Consortium for Blood Pressure., McIntosh, A.M., Gale, C.R., & Deary, I.J. (2016). Molecular genetic contributions to social deprivation and household income in UK Biobank. Current Biology, 26(22), 3083-3089.


Hill, W.D. (2016). FAQ for ‘Molecular genetic contributions to social deprivation and household income in UK Biobank’ by Hill et al. CCACE.


Hill, W.D., Davies, G., Liewald, D.C., Payton, A., McNeil, C.J., Whalley, L.J., Horan, M., Ollier, W. Starr, J.M. Pendleton., N. Hansell, N.K. Montgomery., G.W. Medland, S.E., Martin, N.G., Wright, M.J., Bates, T.C., & Deary, I.J. (2016). Examining non-syndromic autosomal recessive intellectual disability (NS-ARID) genes for an enriched association with intelligence differences. Intelligence, 54, 80-89.


Marioni, R. E., Ritchie, S. J., Joshi, P. K., Hagenaars, S. P., Okbay, A., Fischer, K., Adams, M. J., Hill, W. D., ... & Deary, I.J. (2016). Genetic variants linked to education predict longevity. Proceedings of the National Academy of Sciences, 113(47), 13366-13371.


Bakshi, A., Zhu, Z., Vinkhuyzen, A.A., Hill, W.D., McRae, A.F., Visscher, P.M., & Yang, J. (2016). Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits. Scientific Reports, 6, 32894.


Harris, S. E., Hagenaars, S. P., Davies, G., Hill, W.D., Liewald, D. C., Ritchie, S. J., ... & Deary, I.J. (2016). Molecular genetic contributions to self-rated health. International journal of epidemiology, 46(3), 994-1009.


Eicher, J.D., 15 authors, Hill, W.D., & 95 authors, & Johnson, A.D. (2016). Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. The American Journal of Human Genetics, 99(1), 40-55.


Chami, N., 18 authors, Hill, W.D., & 92 authors, Lettre, G. (2016). Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. The American Journal of Human Genetics, 99(1), 8-21.


Tajuddin, S. M., 5 authors, Hill, W.D., & 89 authors, & Auer, P.L. (2016). Large-Scale Exome-wide Association Analysis Identifies Loci for White Blood Cell Traits and Pleiotropy with Immune-Mediated Diseases. The American Journal of Human Genetics, 99(1), 22-39.


Hagenaars, S. P., Harris, S. E., Davies, G., Hill, W.D., 19 authors, & Deary, I.J. (2016). Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia. Molecular Psychiatry, 21(11), 1624.


Gale, C. R., Hagenaars, S. P., Davies, G., Hill, W. D., Liewald, D. C., Cullen, B., ... & Smith, D. J. (2016). Pleiotropy between neuroticism and physical and mental health: findings from 108 038 men and women in UK Biobank. Translational psychiatry, 6(4), e791.


Hill, W.D., Davies, G., CHARGE Cognitive Working Group., Liewald, D.C., McIntosh, A.M., & Deary, I.J. (2015). Age-Dependent Pleiotropy Between General Cognitive Function and Major Psychiatric Disorders. Biological Psychiatry, 80(4), 266-273.


Johnson, M. R., Shkura, K., Langley, S.R., Delahaye-Duriez, A., Srivastava, P., Hill, W.D., 27 authors, Petretto, E. (2015). Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease. Nature Neuroscience, 19(2), 223.


Davies, 26 authors, Hill, W.D., 100 authors, & Deary, I.J. (2015). Genetic contributions to variation in general cognitive function: a meta-analysis of genome-wide association studies in the CHARGE consortium (N=53 949). Molecular Psychiatry, 20(2), 183.


Lopez, L.M., Hill, W.D., 21 authors, & Wardlaw, J.M. (2015). Genes From a Translational Analysis Support a Multifactorial Nature of White Matter Hyperintensities. Stroke, 46(2), 341-347.


Hill, W.D., de Leeuw, C., Davies, G., Liewald, D.C.M., Payton, A., Craig, L.C., Whalley, L.J., Horan, M., Ollier, W., Starr, J.M., Pendleton, N., Posthuma, D., Bates, & Deary, I.J. (2014). Functional Gene Group Analysis Indicates No Role for Heterotrimeric G Proteins in Cognitive Ability. PlosOne, 9(3), e91690.


Hill, W.D., Davies, G., Van De Lagemaat, L.N., Christoforou, A., Marioni, R.E., Fernandes, C.P.D., Liewald, D.C., Croning, M.D.R., Payton, A., Craig, L.C.A, Whalley, L.J., Horan, M., Ollier, W., Hansell, N.K., Wright, M.J., Martin. N.G., Montgomery, W., Steen, V.M., Le Hellard, S., Espeseth, T., Lundervold, A.J., Reinvang, I., Starr, J.M., Pendleton, N., Grant, S.G.N., Bates, T.C., & Deary, I.J. (2014). Human cognitive ability is influenced by genetic variation in components of postsynaptic signalling complexes assembled by NMDA receptors and MAGUK proteins. Translational Psychiatry, 4(1), e341.


Hill, W.D., Saville, C.W., Kiely, S., Roberts, M.V., Boehm, S.G., Haenschel, C., & Klein, C. (2011). Early electro-cortical correlates of inspection time task performance. Intelligence, 39(5), 370-377.

Research summary

Intelligence, genetics, gene-set analysis.