Colin is based in the Centre for Cognitive Ageing and Cognitive Epidemiology, within the Psychology Department. He works with UK Biobank neuroimaging data and Lothian Birth Cohort Study 1936 as part of a 5-year NIH grant to investigate the brain's structural connectome in relation to cognitive function, health and genes.
Colin's field of work is connectomics, the study of the connectome, which seeks to map the connections of the brain as a network. Using imaging data obtained from diffusion MRI and whole-brain tractography, connectome methods are used to map the collective wiring of many trillions of axonal nerve fibres across the brain. The connectome approach provides tools to ask neuroscientific questions concerned with healthy and pathological brain organisation. This approach may also provide evidence on how cerebral white matter underlies cognitive function.
The effect of network thresholding and weighting on structural brain networks in the UK Biobank
Associations between vascular risk factors and brain MRI indices in UK Biobank
Reduced structural connectivity within a prefrontal-motor-subcortical network in amyotrophic lateral sclerosis
Test-retest reliability of structural brain networks from diffusion MRI
Structural Brain Networks in Amyotrophic Lateral Sclerosis