Andrea Caporali

Chancellor's Fellow

  • Centre for Cardiovascular Science

Contact details

Address

Street

Queen's Medical Research Institute
47 Little France Crescent
Edinburgh BioQuarter

City
Edinburgh
Post code
EH16 4TJ

Research summary

My lab aims to understand the importance and role of non-coding RNA in the pathophysiology of vascular diseases and during vascular regeneration. Non-coding RNAs have attracted considerable attention in the field of vascular research. What we still don’t understand fully is how their critical regulatory elements target multiple functionally related genes. We use a combination of transcriptomic, functional genomic and imaging approaches to depict the role of newly identified non-coding RNA during angiogenesis and vascular regeneration.  By performing loss-of-function studies and pre-clinical imaging we are able to characterize the impact of selected non-coding RNA and their target genes on capillary growth or collateralization in vitro and in vivo. Overall, we look to link the function of newly identified non-coding RNA with their molecular signalling and to describe their wider involvement in vascular regeneration.

Research activities

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View all 69 publications on Research Explorer