Dr Atul Anand
Senior Clinical Research Fellow
- Centre for Cardiovascular Science
- HighSTEACS Research Group
Contact details
- Email: atul.anand@ed.ac.uk
Research summary
My main research interests are in the use of routine health data to improve outcomes for older people. In my PhD this focussed on cardiovascular disease and frailty, but my interests have expanded to cover a broader range of conditions. This is in line with my clinical work as a consultant geriatrician at the Royal Infirmary of Edinburgh.
I have been a co-investigator on the HighSTEACS and HiSTORIC cluster randomised trials and am a passionate advocate for these methodologies to improve representation and inclusion of older people in clinical trials. I am the clinical data lead for the DataLoch programme – a data repository of health and social care data in South East Scotland – that will dramatically improve the quality and access to routinely linked data.
In keeping with these interests, I am developing a routine electronic health record hospital screening tool for frailty, based on data entered in the normal admission process for older adults. This is available real-time and has recently been adopted to help triage patient care at Royal Infirmary of Edinburgh in response to the COVID-19 pandemic. An evaluation of the impact of this approach is ongoing.
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Clinical burden, risk factor impact and outcomes following myocardial infarction and stroke: a 25-year individual patient level linkage study
In:
The Lancet regional health. Europe
DOI: https://doi.org/10.1016/j.lanepe.2021.100141
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Cardiac troponin thresholds and kinetics to differentiate myocardial injury and myocardial infarction
In:
Circulation
Research output: Contribution to Journal › Article (Accepted/In press) -
Implementation of High-Sensitivity Cardiac Troponin in Patients with Renal Impairment
In:
JAMA Internal Medicine
DOI: https://doi.org/10.1001/jamainternmed.2021.1184
Research output: Contribution to Journal › Letter (E-pub ahead of print) -
The Ambulance Cardiac Chest Pain Evaluation in Scotland Study (ACCESS): A Prospective Cohort Study
In:
Annals of Emergency Medicine
DOI: https://doi.org/10.1016/j.annemergmed.2021.01.012
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Diagnostic performance of the combined nasal and throat swab in patients admitted to hospital with suspected COVID-19
In:
BMC Infectious Diseases
DOI: https://doi.org/10.1186/s12879-021-05976-1
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Serum transthyretin and risk of cognitive decline and dementia: 22-year longitudinal study.
In:
Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology
DOI: https://doi.org/10.1007/s10072-021-05191-5
Research output: Contribution to Journal › Article (E-pub ahead of print) -
Predicting readmission and death after hospital discharge: a comparison of conventional frailty measurement with an electronic health record-based score
In:
Age and Ageing
DOI: https://doi.org/10.1093/ageing/afab043
Research output: Contribution to Journal › Article (E-pub ahead of print) -
High-Sensitivity Cardiac Troponin on Presentation to Rule Out Myocardial Infarction: A Stepped-Wedge Cluster Randomized Controlled Trial.
In:
Circulation
DOI: https://doi.org/10.1161/circulationaha.120.052380
Research output: Contribution to Journal › Article (Published) -
How to design a hypertension treatment trial that informs care of older people with frailty: a survey of clinicians in Ireland and the UK
In:
Age and Ageing
DOI: https://doi.org/10.1093/ageing/afaa198
Research output: Contribution to Journal › Article (Published) -
Serial troponin measurements to monitor risk & response to endothelin-A antagonism in chronic kidney disease Research Letter
In:
Nephrology dialysis transplantation, vol. 36
DOI: https://doi.org/10.1093/ndt/gfaa214
Research output: Contribution to Journal › Letter (E-pub ahead of print) -
High-sensitivity cardiac troponin on presentation to rule out myocardial infarction: a stepped-wedge cluster randomised controlled trial
DOI: https://doi.org/10.1101/2020.09.06.20189308
Research output: › Working paper (Published) -
Performance of the GRACE 2.0 score in patients with type 1 and type 2 myocardial infarction
In:
European Heart Journal, vol. n/a, pp. 1-10
DOI: https://doi.org/10.1093/eurheartj/ehaa375
Research output: Contribution to Journal › Article (Published) -
Incidence, microbiology and outcomes in patient hospitalized with infective endocarditis
In:
Circulation
DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.044913
Research output: Contribution to Journal › Article (Published) -
Exploring Patient Experience of Chest Pain Before and After Implementation of an Early Rule-Out Pathway for Myocardial Infarction: A Qualitative Study
(12 pages)
In:
Annals of Emergency Medicine, vol. 75, pp. 502-513
DOI: https://doi.org/10.1016/j.annemergmed.2019.11.012
Research output: Contribution to Journal › Article (Published) -
Frailty assessment and risk prediction by GRACE score in older patients with acute myocardial infarction
In:
BMC Geriatrics, vol. 20
DOI: https://doi.org/10.1186/s12877-020-1500-9
Research output: Contribution to Journal › Article (Published) -
Risk Stratification Using High-Sensitivity Cardiac Troponin T in Patients With Suspected Acute Coronary Syndrome
(3 pages)
In:
Journal of the American College of Cardiology, vol. 75, pp. 985-987
DOI: https://doi.org/10.1016/j.jacc.2019.12.036
Research output: Contribution to Journal › Article (Published) -
High-sensitivity cardiac troponin and the universal definition of myocardial infarction
(11 pages)
In:
Circulation, vol. 141, pp. 161–171
DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.042960
Research output: Contribution to Journal › Article (Published) -
Diagnosing myocardial infarction in the era of high-sensitivity troponin: the High-STEACS trial
In:
Cardiovascular Research
DOI: https://doi.org/10.1093/cvr/cvz274
Research output: Contribution to Journal › Article (E-pub ahead of print) -
High-sensitivity troponin and the application of risk stratification thresholds in patients with suspected acute coronary syndrome
In:
Circulation, vol. 140, pp. 1557–1568
DOI: https://doi.org/10.1161/CIRCULATIONAHA.119.042866
Research output: Contribution to Journal › Article (Published) -
Sex-Specific Thresholds of High-Sensitivity Troponin in Patients With Suspected Acute Coronary Syndrome
(12 pages)
In:
Journal of the American College of Cardiology, vol. 74, pp. 2032-2043
DOI: https://doi.org/10.1016/j.jacc.2019.07.082
Research output: Contribution to Journal › Article (Published)