21 Jul 21. Featured Paper
Reproducibility of retinal vascular phenotypes obtained with optical coherence tomography angiography: importance of vessel segmentation
Optical coherence tomography angiography (OCTA) is a non-invasive imaging method that can visualize the finest vascular networks in the human retina.
To characterize & distinguish OCTA images from different pathologies, it is important to identify quantitative metrics & phenotypes that have high reproducibility & are not overly susceptible to the effects of imaging artifacts.
This paper demonstrates the reproducibility of several recently demonstrated candidate OCTA quantitative metrics: mean curvature & tortuosity of the whole, foveal, superior, nasal, inferior, & temporal regions; foveal & parafoveal vessel skeleton density; & finally, foveal avascular zone area & acircularity index.
This paper also highlights the importance of vessel segmentation choice on reproducibility using two different segmentation methods: optimally oriented flux & Frangi filter.
- OCTA imaging
- Retinal vascular phenotype
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Featured paper: Reproducibility of retinal vascular phenotypes obtained with optical coherence tomography angiography: importance of vessel segmentation