ASPIRED Study
Multi-centre open label randomised controlled trial of immediate enhanced ambulatory ECG monitoring versus standard monitoring in acute unexplained syncope patients: The ASPIRED study.
Syncope (sudden loss of consciousness also known as blackout or fainting) causes over 600,000 people to visit emergency departments every year in the UK. Often, by the time the patient is seen by the medical team they have fully recovered making it hard to diagnose the underlying problem.
A mobile heart ECG monitoring device has recently been developed (BodyGuardian Mini; Preventice Solutions). This device can record the patients heartbeat and heart electrical rhythm tracing for up to 14 days. By applying the mobile heart monitor after attendance at the emergency department we hope to have a better chance of diagnosing the underlying problem that caused the syncope.
Chief Investigator: Dr Matt Reed
Number and location of participating sites (by region/ country): 25 UK sites
EudraCT number: n/a
ISRCTN number: ID number 52042 https://hub.crncc.nihr.ac.uk/
Funder: British Heart Foundation
Start and End date
Of grant award: 01 Aug 2022 – 31 Jul 2025
Of recruitment: 30 March 2022 – 30 August 2023
Current Status: In set up
Trial Website: https://www.emergeresearch.org/trial/aspired/
Study Protocol:
Patient Information Sheets:
SAP, HEAP and DSP:
Please follow this link to view the ASPIRED Preventice Participant Video:
https://vimeo.com/736584068/d52656afb6
Health Economics: School of Health and Related Research, University of Sheffield
Regent Court, 30 Regent Street, Sheffield
Email: ASPIRED.Study@ed.ac.uk
UK GDPR Privacy Statement: As part of the PIS (currently pending approval)
Participant area:
Sponsor: Accord, https://www.accord.scot/
Chief Investigator:
Dr Matt Reed, Consultant and Honorary Senior Lecturer in Emergency Medicine, Emergency Dept., Royal Infirmary of Edinburgh, 51 Little France Crescent, Edinburgh, EH16 4SA.
matthew.reed@nhslothian.scot.nhs.uk
Trial Manager:
Lynn Dinsmore, ECTU, University of Edinburgh, Level 2, NINE Edinburgh BioQuarter, 9 Little France Road, Edinburgh EH16 4UX Lynn.Dinsmore@ed.ac.uk
ECTU involvement: Trial Management, Statistics, Database and randomisation service