Synapses, Circuits and Behaviour
The Research Theme is studying the cellular and circuit mechanisms underpinning nervous system functions.
Neurons are the fundamental building blocks of the nervous system and unravelling the mechanisms that regulate neuronal excitability, communication and plasticity is key to understanding how the nervous system controls complex behaviours.
In this research theme, investigators exploit advanced imaging, electrophysiological, molecular genetic and quantitative behavioural approaches to understand the cellular and circuit mechanisms underpinning nervous system functions such as sensory perception, memory formation and the control of complex, adaptable behaviours in the healthy and diseased brain.
Our aim is to translate fundamental discoveries, through development of animal- and human-based models, to generate transformative therapeutic interventions for disorders that affect nervous system function.
Theme Lead: Prof Ian Duguid
|Baranovic, Jelena||Structure and function of neuroreceptors, synaptic transmission, ion channels, electrophysiology|
|Clemens, Ann||Neural circuits of social behaviour|
|Cobb, Stuart||Novel therapies for neurodevelopmental disorders|
|Cousin, Michael||Presynaptic Cell Biology|
|Daw, Michael||Developmental Physiology of the Barrel Cortex|
|Duguid, Ian||Neural circuits and motor behaviour|
|Evans, Mark||Calcium signalling & hypoxia-response coupling|
|Fleetwood-Walker, Susan||Molecular mechanisms of pain and analgesia|
|Gillingwater, Tom||New therapies for neurodegenerative diseases|
|Gonzalez-Sulser, Alfredo||Network analysis and therapeutic strategies in epilepsy|
|Greiss, Sebastian||Genetic code expansion and neural circuits|
|Jones, Ross||Structure and function of the human neuromuscular junction|
|Kind, Peter||Disorders of Brain Development|
|Luksys, Gedi||Computational cognitive neuroscience|
|Mitchell, Rory||Receptor-mediated signal transduction|
|Morris, Richard||Neurobiology of learning and memory|
|Nolan, Matthew||Neural circuits and computation|
|Osterweil, Emily||mRNA translation and synaptic connections|
|Synaptic repair mechanisms for the diseased brain|
|Ribchester, Richard||Neuromuscular connections|
|Rochefort, Nathalie||Neuronal processing of visual information|
|Smillie, Karen||Synaptic vesicle recycling|
|Stefan, Melanie||Understanding of learning and memory|
|Sürmeli, Gülşen||Neural circuits of memory|
|Torsney, Carole||Somatosensory plasticity|
|Wood, Emma||Memory and Space|
|Wyllie, David||Physiology and pharmacology of ion channels|