Jose L. Garcia-Perez is a Chancellor’s Fellow within the Medical and Developmental Research Section at the MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine (IGMM) at the University of Edinburgh. He studied a B.Sc. in Pharmacy at the University of Granada, Spain. He received his Ph.D. in Molecular Biology at the Spanish National Research Council (CSIC) in 2003, at Instituto de Parasitologia y Biomedicina Lopez-Neyra, Granada, Spain. His PhD thesis analysed active pieces of mobile DNA on Trypanosoma, and he characterized the first RNaseH domain present in a LINE element from Trypanosoma cruzi. In late 2003, Jose moved to the USA to carry out postdoctoral research in the laboratory of John V. Moran (University of Michigan Medical School), where he studied how human LINE-1 retrotransposons are regulated and established a new model to study retrotransposition using human embryonic stem cells. In 2007, he was promoted to Faculty Research Investigator in the Department of Human Genetics at the University of Michigan Medical School. Jose returned to Spain in 2008, joining the Andalusian Health System to establish an independent research group investigating how active human LINE-1 retrotransposons impact the human genome. He was a Group Leader at the Andalusian Center for Genomics and Oncological Studies (GENYO, Granada, Spain) and held an Associate Professor position within CSIC. In January 2012, the Howard Hughes Medical Institute appointed Jose as an International Early Career Scientist. Jose was awarded a Chancellor’s Fellowship from the University of Edinburgh and joined the MRC Human Genetics Unit in 2016. His laboratory aims to study how active LINE-1 retrotransposons are regulated and what could be the functional consequences of their mobilization in selected somatic tissues.