Dr Dáša Longman (MSc Biotechnology, PhD Molecular Biology)

Senior Investigator Scientist

MRC Human Genetics Unit
Institute of Genetics and Cancer
University of Edinburgh

Tel: 0131 651 8688
Email: dasa.longman@ed.ac.uk

MRC Human Genetics Unit

Street: MRC Human Genetics Unit
Western General Hospital
Crewe Road
City: Edinburgh
Post code: EH4 2XU

Publications

A sensitive and affordable multiplex RT-qPCR assay for SARS-CoV-2 detection 15 Dec 2020 In: PLoS Biology, vol. 18, pp. e3001030
DOI: https://doi.org/10.1371/journal.pbio.3001030
Research output: Contribution to Journal › Article (E-pub ahead of print)
Identification of a localized Nonsense-Mediated Decay pathway at the Endoplasmic Reticulum 2 Jul 2020 In: Genes and Development, vol. 34, pp. 1075-1088
DOI: https://doi.org/10.1101/gad.338061.120
Research output: Contribution to Journal › Article (E-pub ahead of print)
Compound heterozygous variants in NBAS as a cause of atypical osteogenesis imperfecta. (10 pages) Jan 2017 In: Bone, vol. 94, pp. 65-74
DOI: https://doi.org/10.1016/j.bone.2016.10.023
Research output: Contribution to Journal › Article (Published)
Mechanism and regulation of the nonsense-mediated decay pathway (13 pages) 14 Jan 2016 In: Nucleic Acids Research, pp. 1483-1495
DOI: https://doi.org/10.1093/nar/gkw010
Research output: Contribution to Journal › Article (Published)
Identification and characterization of novel factors that act in the nonsense‐mediated mRNA decay pathway in nematodes, flies and mammals 1 Jan 2015 In: EMBO Reports, vol. 16, pp. 71-78
DOI: https://doi.org/10.15252/embr.201439183
Research output: Contribution to Journal › Article (Published)
DHX34 and NBAS form part of an autoregulatory NMD circuit that regulates endogenous RNA targets in human cells, zebrafish and Caenorhabditis elegans (13 pages) 1 Sep 2013 In: Nucleic Acids Research, vol. 41, pp. 8319-31
DOI: https://doi.org/10.1093/nar/gkt585
Research output: Contribution to Journal › Article (Published)
Dhx34 and Nbas function in the NMD pathway and are required for embryonic development in zebrafish (9 pages) 2011 In: Nucleic Acids Research, vol. 39, pp. 3686-94
DOI: https://doi.org/10.1093/nar/gkq1319
Research output: Contribution to Journal › Article (Published)
Chapter 7. Nonsense-mediated mRNA decay in Caenorhabditis elegans (16 pages) 2008 In: Methods in enzymology, vol. 449, pp. 149-64
DOI: https://doi.org/10.1016/S0076-6879(08)02407-5
Research output: Contribution to Journal › Article (Published)
NONSENSE-MEDIATED MRNA DECAY IN CAENORHABDITIS ELEGANS (16 pages) 2008
DOI: https://doi.org/10.1016/S0076-68979(08)02407-5
Research output: › Other chapter contribution (Published)
Identification and characterization of RED120: a conserved PWI domain protein with links to splicing and 3'-end formation (11 pages) 26 Jun 2007 In: FEBS Letters, vol. 581, pp. 3087-97
DOI: https://doi.org/10.1016/j.febslet.2007.05.066
Research output: Contribution to Journal › Article (Published)
Mechanistic insights and identification of two novel factors in the C. elegans NMD pathway (11 pages) 2007 In: Genes and Development, vol. 21, pp. 1075-85
DOI: https://doi.org/10.1101/gad.417707
Research output: Contribution to Journal › Article (Published)
Proteomic analysis of SRm160-containing complexes reveals a conserved association with cohesin (10 pages) 23 Dec 2005 In: Journal of Biological Chemistry, vol. 280, pp. 42227-36
DOI: https://doi.org/10.1074/jbc.M507410200
Research output: Contribution to Journal › Article (Published)
An evolutionarily conserved role for SRm160 in 3'-end processing that functions independently of exon junction complex formation (8 pages) 7 Nov 2003 In: Journal of Biological Chemistry, vol. 278, pp. 44153-60
DOI: https://doi.org/10.1074/jbc.M306856200
Research output: Contribution to Journal › Article (Published)
The Ref/Aly proteins are dispensable for mRNA export and development in Caenorhabditis elegans (11 pages) 2003 In: RNA, vol. 9, pp. 881-91
DOI: https://doi.org/10.1261/rna.5420503
Research output: Contribution to Journal › Article (Published)
Multiple roles of the SR protein family in splicing regulation (26 pages) 2003 In: Progress in molecular and subcellular biology, vol. 31, pp. 33-58
Research output: Contribution to Journal › Article (Published)
Mammalian PRP4 kinase copurifies and interacts with components of both the U5 snRNP and the N-CoR deacetylase complexes (16 pages) 2002 In: Molecular and Cellular Biology, vol. 22, pp. 5141-56
DOI: https://doi.org/10.1128/MCB.22.14.5141-5156.2002
Research output: Contribution to Journal › Article (Published)
Multiple interactions between SRm160 and SR family proteins in enhancer-dependent splicing and development of C. elegans (11 pages) 2001 In: Current Biology, vol. 11, pp. 1923-33
DOI: https://doi.org/10.1016/S0960-9822(01)00589-9
Research output: Contribution to Journal › Article (Published)
Functional characterization of SR and SR-related genes in Caenorhabditis elegans (13 pages) 2000 In: EMBO Journal, vol. 19, pp. 1625-37
DOI: https://doi.org/10.1093/emboj/19.7.1625
Research output: Contribution to Journal › Article (Published)

View all 18 publications on Research Explorer

This article was published on 1 May, 2024

Dr Dáša Longman (MSc Biotechnology, PhD Molecular Biology)

Contact details

Address

Publications